4-(4-pyridyl)-5-(4-fluorophenyl)-1-trityl-2-iodo-1H-imidazole

Base Information

• Chemical Name: 4-(4-pyridyl)-5-(4-fluorophenyl)-1-trityl-2-iodo-1H-imidazole
• CAS No.: 1201526-47-7
• Molecular Formula: C₃₃H₂₃FIN₃
• Molecular Weight: 607.469
• Mol file: 1201526-47-7.mol

Synonyms:4-(4-pyridyl)-5-(4-fluorophenyl)-1-trityl-2-iodo-1H-imidazole

Chemical Property of 4-(4-pyridyl)-5-(4-fluorophenyl)-1-trityl-2-iodo-1H-imidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(4-pyridyl)-5-(4-fluorophenyl)-1-trityl-2-iodo-1H-imidazole

There total 1 articles about 4-(4-pyridyl)-5-(4-fluorophenyl)-1-trityl-2-iodo-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

4-(4-pyridyl)-5-(4-fluorophenyl)-1-trityl-1H-imidazole (1201526-45-5) → 4-(4-pyridyl)-5-(4-fluorophenyl)-1-trityl-2-iodo-1H-imidazole (1201526-47-7)

Guidance literature:

With n-butyllithium; iodine; In tetrahydrofuran; hexane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.bmcl.2009.09.094

Reference yield: 83.0%

4-(4-pyridyl)-5-(4-fluorophenyl)-1-trityl-2-iodo-1H-imidazole (1201526-47-7) → 4-(4-pyridyl)-5-(4-fluorophenyl)-2-iodo-1H-imidazole (1201526-49-9)

Guidance literature:

With trifluoroacetic acid; In tetrahydrofuran; water; for 4h; Inert atmosphere;

DOI:10.1016/j.bmcl.2009.09.094

upstream raw materials:

4-(4-pyridyl)-5-(4-fluorophenyl)-1-trityl-1H-imidazole

Downstream raw materials:

4-(4-pyridyl)-5-(4-fluorophenyl)-2-iodo-1H-imidazole