5-(4-fluorophenoxy)-1-oxynicotinonitrile

Base Information

Chemical Name:5-(4-fluorophenoxy)-1-oxynicotinonitrile
CAS No.:1336910-76-9
Molecular Formula:C₁₂H₇FN₂O₂
Molecular Weight:230.198
Hs Code.:

Synonyms:5-(4-fluorophenoxy)-1-oxynicotinonitrile

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Chemical Property of 5-(4-fluorophenoxy)-1-oxynicotinonitrile

Chemical Property:

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Technology Process of 5-(4-fluorophenoxy)-1-oxynicotinonitrile

There total 3 articles about 5-(4-fluorophenoxy)-1-oxynicotinonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1336910-75-8
5-(4-fluorophenoxy)nicotinonitrile

: 1336910-76-9
5-(4-fluorophenoxy)-1-oxynicotinonitrile

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; at 20 ℃; for 5h; Reflux;

Reference yield:

: 371-41-5
4-Fluorophenol

: 1336910-76-9
5-(4-fluorophenoxy)-1-oxynicotinonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / dimethyl sulfoxide; mineral oil / 16 h / 120 °C / Inert atmosphere

2: 3-chloro-benzenecarboperoxoic acid / 5 h / 20 °C / Reflux

With sodium hydride; 3-chloro-benzenecarboperoxoic acid; In dimethyl sulfoxide; mineral oil;

Reference yield:

: 35590-37-5
5-bromopyridine-3-carbonitrile

: 1336910-76-9
5-(4-fluorophenoxy)-1-oxynicotinonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / dimethyl sulfoxide; mineral oil / 16 h / 120 °C / Inert atmosphere

2: 3-chloro-benzenecarboperoxoic acid / 5 h / 20 °C / Reflux

With sodium hydride; 3-chloro-benzenecarboperoxoic acid; In dimethyl sulfoxide; mineral oil;