Diethyl 2-acetamido-2-(1-methylindol-3-ylmethyl)malonate

Base Information

Chemical Name:Diethyl 2-acetamido-2-(1-methylindol-3-ylmethyl)malonate
CAS No.:6976-19-8
Molecular Formula:C19H24 N2 O5
Molecular Weight:360.41
Hs Code.:
European Community (EC) Number:661-349-8
NSC Number:24950
DSSTox Substance ID:DTXSID60989923
Wikidata:Q82979202

Synonyms:6976-19-8;NSC24950;DTXSID60989923;DIETHYL 2-ACETAMIDO-2-(1-METHYLINDOL-3-YLMETHYL)MALONATE;NSC-24950;AKOS024325239;N-{1,3-Diethoxy-2-[(1-methyl-1H-indol-3-yl)methyl]-1,3-dioxopropan-2-yl}ethanimidic acid

Suppliers and Price of Diethyl 2-acetamido-2-(1-methylindol-3-ylmethyl)malonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Diethyl 2-acetamido-2-(1-methylindol-3-ylmethyl)malonate

Chemical Property:

Vapor Pressure:7.04E-12mmHg at 25°C
Boiling Point:543.6°C at 760 mmHg
Flash Point:282.6°C
Density:1.18g/cm³
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:360.16852187
Heavy Atom Count:26
Complexity:518

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(CC1=CN(C2=CC=CC=C21)C)(C(=O)OCC)NC(=O)C

Technology Process of Diethyl 2-acetamido-2-(1-methylindol-3-ylmethyl)malonate

There total 1 articles about Diethyl 2-acetamido-2-(1-methylindol-3-ylmethyl)malonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5379-97-5
acetylamino-indol-3-ylmethyl-malonic acid diethyl ester

: 80-48-8
methyl p-toluene sulfonate

: 6976-19-8
acetylamino-(1-methyl-indol-3-ylmethyl)-malonic acid diethyl ester

Guidance literature:: With potassium carbonate; xylene;
DOI:10.1021/jo01098a618

Reference yield:

: 6976-19-8
acetylamino-(1-methyl-indol-3-ylmethyl)-malonic acid diethyl ester

: 26988-72-7
2-amino-3-(1-methyl-1H-indol-3-yl)-propanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: aqueous NaOH

2: 180 - 190 °C / Erhitzen unter Stickstoff

3: aqueous HCl

With hydrogenchloride; sodium hydroxide;
DOI:10.1021/jo01098a618