(R)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol

Base Information

Chemical Name:(R)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol
CAS No.:80655-81-8
Molecular Formula:C₂₀H₁₂Br₂O₂
Molecular Weight:444.122
Hs Code.:29081990
European Community (EC) Number:624-066-0,632-860-3,633-215-9
NSC Number:9772
DSSTox Substance ID:DTXSID80927367
Nikkaji Number:J1.058.424H,J1.909.858C,J618.779J
Wikidata:Q72463924
Mol file:80655-81-8.mol

Synonyms:6,6'-dibromo-(1,1'-binaphthalene)-2,2'-diol

Suppliers and Price of (R)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-6,6''-Dibromo-1,1''-bi-2-naphthol
500mg
$ 65.00

TCI Chemical
(S)-(+)-6,6'-Dibromo-1,1'-bi-2-naphthol >98.0%(HPLC)
1g
$ 136.00

TCI Chemical
(S)-(+)-6,6'-Dibromo-1,1'-bi-2-naphthol >98.0%(HPLC)
5g
$ 408.00

SynChem
(S)-(+)-6,6'-Dibromo-1,1'-bi-naphthol 98+%, 99%ee
1 g
$ 35.00

SynChem
(S)-(+)-6,6'-Dibromo-1,1'-bi-naphthol 98+%, 99%ee
5 g
$ 130.00

Strem Chemicals
(S)-(+)-6,6'-Dibromo-1,1'-bi-2-naphthol, 98% (99% ee)
2g
$ 233.00

Strem Chemicals
(S)-(+)-6,6'-Dibromo-1,1'-bi-2-naphthol, min. 98%
2g
$ 359.00

Strem Chemicals
(S)-(+)-6,6'-Dibromo-1,1'-bi-2-naphthol, min. 98%
500mg
$ 120.00

Strem Chemicals
(S)-(+)-6,6'-Dibromo-1,1'-bi-2-naphthol, 98% (99% ee)
500mg
$ 78.00

Sigma-Aldrich
6,6′-Dibromo-1,1′-bi-2-naphthol 97%
1 g
$ 63.30

Total 31 raw suppliers

Chemical Property of (R)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol

Chemical Property:

Appearance/Colour:white to light yellow crystal powder
Melting Point:195-199 °C(lit.)
Refractive Index:1.4947 (estimate)
Boiling Point:546.2 °C at 760 mmHg
PKA:7.78±0.50(Predicted)
Flash Point:284.1 °C
PSA：40.46000
Density:1.761 g/cm³
LogP:6.59620
Storage Temp.:Inert atmosphere,Room Temperature
Solubility.:slightly sol. in Tetrahydrofuran
XLogP3:6.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:443.91836
Heavy Atom Count:24
Complexity:405

Purity/Quality:

99% ^*data from raw suppliers

(S)-6,6''-Dibromo-1,1''-bi-2-naphthol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi,Xn
Hazard Codes:Xi,Xn
Statements: 36/37/38-22
Safety Statements: 26-36-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=CC(=C2C3=C(C=CC4=C3C=CC(=C4)Br)O)O)C=C1Br
Uses (S)-(+)-6,6′-Dibromo-1,1′-bi-2-naphthol may be used in the synthesis of (2R,3S)-3-phenylisoserine hydrochloride. It may also be used in the synthesis of BINOL-derived chiral ligands with aryl substituents in the 6,6-positions. [BINOL=1,1′-bi-2-naphthol]

Technology Process of (R)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol

There total 13 articles about (R)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 18531-99-2
(S)-[1,1']-binaphthalenyl-2,2'-diol

: 13185-00-7,65283-60-5,79082-80-7,80655-81-8
(S)-6,6'-dibromo-1,1'-bi-2-naphthol

Guidance literature:: With bromine; In dichloromethane; at -78 ℃; Inert atmosphere;

Reference yield: 99.0%

: 18531-99-2,602-09-5,18531-94-7
1,1’-bi-2-naphthol

: 80655-81-8,65283-60-5,13185-00-7
(R)-6,6'-dibromo-1,1'-binaphthol

Guidance literature:: With bromine; In dichloromethane; at 20 ℃;

Reference yield: 48.0%

: 79082-80-7
(S)-6,6'-dibromo-1,1'-binaphthalene-2,2'-diol

: 65283-60-5
(R)-6,6'-dibromo-1,1'-binaphth-2-ol

: 13185-00-7,65283-60-5,79082-80-7,80655-81-8
(S)-6,6'-dibromo-1,1'-bi-2-naphthol

Guidance literature:: (S)-6,6'-dibromo-1,1'-binaphthalene-2,2'-diol; With dimethylsulfide borane complex; In tetrahydrofuran; toluene; at 80 ℃; for 0.5h; Inert atmosphere;

With quinidine; In tetrahydrofuran; hexane; at 80 ℃; for 12h; Inert atmosphere;

With hydrogenchloride; In water; at 20 ℃; for 0.5h; Inert atmosphere;
DOI:10.1021/acs.joc.0c00494