(S)-2-Chloro-3-methylbutyric acid

Base Information

Chemical Name:(S)-2-Chloro-3-methylbutyric acid
CAS No.:26782-74-1
Molecular Formula:C₅H₉ClO₂
Molecular Weight:136.578
Hs Code.:29159000
European Community (EC) Number:624-356-7
DSSTox Substance ID:DTXSID101294792
Nikkaji Number:J970.114A
Mol file:26782-74-1.mol

Synonyms:(S)-2-Chloro-3-methylbutyric acid;26782-74-1;(S)-2-chloro-3-methylbutanoic acid;(2S)-2-chloro-3-methylbutanoic acid;(S)-2-Chloroisovaleric Acid;(2S)-2-Chloro-3-methyl-butanoic acid;MFCD00067109;S-2-chloro-3-methylbutyric acid;SCHEMBL4970328;DDTJFSPKEIAZAM-BYPYZUCNSA-;TQP0739;DDTJFSPKEIAZAM-BYPYZUCNSA-N;2-Chloro-3-methylbutanoic acid #;DTXSID101294792;(S)-2-chloro-3-methylbutanoicacid;AM9806;(s)-2-chloro-3-methyl-butanoic acid;AKOS015848433;AS-81145;J-016541;QUINAZOLINE,4,6-DICHLORO-2-(4-MORPHOLINYL)-;(S)-2-Chloro-3-methylbutyric acid, technical, >=90% (GC);InChI=1/C5H9ClO2/c1-3(2)4(6)5(7)8/h3-4H,1-2H3,(H,7,8)/t4-/m0/s1

Suppliers and Price of (S)-2-Chloro-3-methylbutyric acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-2-Chloro-3-methylbutyric Acid
50mg
$ 60.00

TCI Chemical
(S)-2-Chloro-3-methylbutyric Acid >98.0%(T)
1g
$ 109.00

TCI Chemical
(S)-2-Chloro-3-methylbutyric Acid >98.0%(T)
5g
$ 353.00

Crysdot
(S)-2-Chloro-3-methylbutanoicacid 97%
5g
$ 198.00

Crysdot
(S)-2-Chloro-3-methylbutanoicacid 97%
1g
$ 61.00

Chem-Impex
(S)-2-Chloro-3-methylbutyricacid,≥98%(Assaybytitration)Hazmat ≥98%(Assaybytitration)
5G
$ 422.82

Chem-Impex
(S)-2-Chloro-3-methylbutyricacid,98%(Assaybytitration) 98%(Assaybytitration)
1G
$ 113.12

Biosynth Carbosynth
(S)-2-Chloro-3-methylbutyric Acid
500 mg
$ 100.00

Biosynth Carbosynth
(S)-2-Chloro-3-methylbutyric Acid
1 g
$ 150.00

Biosynth Carbosynth
(S)-2-Chloro-3-methylbutyric Acid
2 g
$ 250.00

Total 29 raw suppliers

Chemical Property of (S)-2-Chloro-3-methylbutyric acid

Chemical Property:

Vapor Pressure:0.0768mmHg at 25°C
Refractive Index:n20/D 1.443
Boiling Point:210.328 °C at 760 mmHg
PKA:3.02±0.14(Predicted)
Flash Point:81.004 °C
PSA：37.30000
Density:1.159 g/cm³
LogP:1.33440
Storage Temp.:2-8°C
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:136.0291072
Heavy Atom Count:8
Complexity:90.4

Purity/Quality:

99%, ^*data from raw suppliers

(S)-2-Chloro-3-methylbutyric Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): C
Hazard Codes:C
Statements: 34
Safety Statements: 26-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(C(=O)O)Cl
Isomeric SMILES:CC(C)[C@@H](C(=O)O)Cl

Technology Process of (S)-2-Chloro-3-methylbutyric acid

There total 7 articles about (S)-2-Chloro-3-methylbutyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 72-18-4,25609-85-2,7004-03-7,921-10-8
L-valine

: 921-08-4,84918-96-7,91423-85-7,26782-74-1
(S)-2-chloro-3-methylbutyric acid

Guidance literature:: With hydrogenchloride; sodium nitrite; In water; at 0 - 20 ℃; for 5h;
DOI:10.1002/anie.201805770

Reference yield: 86.0%

: 640-68-6,25609-85-2,7004-03-7,921-10-8
D-Val-OH

: 921-08-4,84918-96-7,91423-85-7,26782-74-1
(S)-2-chloro-3-methylbutyric acid

Guidance literature:: With hydrogenchloride; sodium nitrite; In water; at 0 ℃;
DOI:10.1016/j.bmc.2013.11.030

Reference yield:

: 72-18-4,25609-85-2,7004-03-7,921-10-8
L-valine

: 921-08-4,84918-96-7,91423-85-7,26782-74-1
(S)-2-chloro-3-methylbutyric acid

: (R)-2-chloro-3-methylbutanoic acid

Guidance literature:: With hydrogenchloride; sodium nitrite; at 0 ℃; for 6h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1016/0040-4020(96)00757-0