allyl-(3,3-diphenyl-pent-4-enyl)-carbamic acid benzyl ester

Base Information

• Chemical Name: allyl-(3,3-diphenyl-pent-4-enyl)-carbamic acid benzyl ester
• CAS No.: 898528-50-2
• Molecular Formula: C₂₈H₂₉NO₂
• Molecular Weight: 411.544
• Mol file: 898528-50-2.mol

Synonyms:allyl-(3,3-diphenyl-pent-4-enyl)-carbamic acid benzyl ester

Chemical Property of allyl-(3,3-diphenyl-pent-4-enyl)-carbamic acid benzyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of allyl-(3,3-diphenyl-pent-4-enyl)-carbamic acid benzyl ester

There total 5 articles about allyl-(3,3-diphenyl-pent-4-enyl)-carbamic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

allyl-(3,3-diphenyl-pent-4-enyl)-amine (898528-46-6) + benzyl chloroformate (501-53-1,94274-21-2) → allyl-(3,3-diphenyl-pent-4-enyl)-carbamic acid benzyl ester (898528-50-2)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 25 ℃; for 0.5h;

DOI:10.1055/s-2006-926433

Reference yield:

methanesulfonic acid 3,3-diphenyl-pent-4-enyl ester → allyl-(3,3-diphenyl-pent-4-enyl)-carbamic acid benzyl ester (898528-50-2)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol / 50 h / 75 °C

2: 84 percent / Et₃N / tetrahydrofuran / 0.5 h / 25 °C

With triethylamine; In tetrahydrofuran; methanol;

DOI:10.1055/s-2006-926433

Reference yield:

3,3-Diphenyl-dihydro-furan-2-one (956-89-8) → allyl-(3,3-diphenyl-pent-4-enyl)-carbamic acid benzyl ester (898528-50-2)

Guidance literature:

Multi-step reaction with 5 steps

1.1: DIBAL-H / CH₂Cl₂; toluene / 0.5 h / -70 °C

2.1: t-BuOK / tetrahydrofuran / 0.25 h / cooling

2.2: tetrahydrofuran

3.1: Et₃N / CH₂Cl₂ / 2.5 h / 25 °C

4.1: methanol / 50 h / 75 °C

5.1: 84 percent / Et₃N / tetrahydrofuran / 0.5 h / 25 °C

With potassium tert-butylate; diisobutylaluminium hydride; triethylamine; In tetrahydrofuran; methanol; dichloromethane; toluene;

DOI:10.1055/s-2006-926433

upstream raw materials:

allyl-(3,3-diphenyl-pent-4-enyl)-amine

benzyl chloroformate

3,3-Diphenyl-dihydro-furan-2-one

3,3-Diphenyl-tetrahydro-furan-2-ol

Downstream raw materials:

4,4-diphenyl-2,3,4,7-tetrahydro-azepine-1-carboxylic acid benzyl ester