C₂₀H₂₅NO₅

Base Information

• Chemical Name: C₂₀H₂₅NO₅
• CAS No.: 1399361-44-4
• Molecular Formula: C₂₀H₂₅NO₅
• Molecular Weight: 359.422
• Mol file: 1399361-44-4.mol

Synonyms:C₂₀H₂₅NO₅

Chemical Property of C₂₀H₂₅NO₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₂₅NO₅

There total 4 articles about C₂₀H₂₅NO₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

C13H18O6 (1399360-53-2) + benzylamine (100-46-9) → C20H25NO5 (1399361-44-4)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 ℃;

Reference yield:

fumagillol (35903-52-7,128656-25-7,132746-73-7,108102-51-8) → C20H25NO5 (1399361-44-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 4-methylmorpholine N-oxide / tetrapropylammonium perruthennate / dichloromethane / 2.5 h / 20 °C / 3A° sieves

2: sodium periodate / N-benzyl-N,N,N-triethylammonium chloride; ruthenium trichloride / ethyl acetate; water

3: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C

With sodium periodate; 4-methylmorpholine N-oxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; ruthenium trichloride; tetrapropylammonium perruthennate; N-benzyl-N,N,N-triethylammonium chloride; In dichloromethane; water; ethyl acetate;

Reference yield:

dicyclohexylamine (2E,4E,6E,8E)-10-(((3R,4S,5S,6R)-5-methoxy-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-1-oxaspiro[2.5]octan-6-yl)oxy)-10-oxodeca-2,4,6,8-tetraenoate (41567-78-6) → C20H25NO5 (1399361-44-4)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium hydroxide; water / 3 h / 20 °C

2: 4-methylmorpholine N-oxide / tetrapropylammonium perruthennate / dichloromethane / 2.5 h / 20 °C / 3A° sieves

3: sodium periodate / N-benzyl-N,N,N-triethylammonium chloride; ruthenium trichloride / ethyl acetate; water

4: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C

With sodium periodate; water; 4-methylmorpholine N-oxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; sodium hydroxide; ruthenium trichloride; tetrapropylammonium perruthennate; N-benzyl-N,N,N-triethylammonium chloride; In dichloromethane; water; ethyl acetate;

upstream raw materials:

C₁₃H₁₈O₆

benzylamine

fumagillol

dicyclohexylamine (2E,4E,6E,8E)-10-(((3R,4S,5S,6R)-5-methoxy-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-1-oxaspiro[2.5]octan-6-yl)oxy)-10-oxodeca-2,4,6,8-tetraenoate

Refernces