2-{[2-(tert-butyldiphenylsilyloxy)ethoxy]acetoxymethyl}-anthraquinone

Base Information

• Chemical Name: 2-{[2-(tert-butyldiphenylsilyloxy)ethoxy]acetoxymethyl}-anthraquinone
• CAS No.: 1265907-08-1
• Molecular Formula: C₃₅H₃₄O₆Si
• Molecular Weight: 578.737
• Mol file: 1265907-08-1.mol

Synonyms:2-{[2-(tert-butyldiphenylsilyloxy)ethoxy]acetoxymethyl}-anthraquinone

Chemical Property of 2-{[2-(tert-butyldiphenylsilyloxy)ethoxy]acetoxymethyl}-anthraquinone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-{[2-(tert-butyldiphenylsilyloxy)ethoxy]acetoxymethyl}-anthraquinone

There total 3 articles about 2-{[2-(tert-butyldiphenylsilyloxy)ethoxy]acetoxymethyl}-anthraquinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

2-[2-(tert-butyldiphenylsilyloxy)ethoxy]acetic acid (1265907-07-0) + 2-Hydroxymethylanthraquinone (17241-59-7) → 2-{[2-(tert-butyldiphenylsilyloxy)ethoxy]acetoxymethyl}-anthraquinone (1265907-08-1)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 - 20 ℃;

DOI:10.1002/anie.201005161

Reference yield:

2-[2-(tert-butyldiphenylsilyloxy)ethoxy]ethanal → 2-{[2-(tert-butyldiphenylsilyloxy)ethoxy]acetoxymethyl}-anthraquinone (1265907-08-1)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / water; tert-butyl alcohol / 0 - 20 °C

2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0 - 20 °C

With dmap; sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; water; tert-butyl alcohol;

DOI:10.1002/anie.201005161

Reference yield:

2-(2-((tert-butyldiphenylsilyl)oxy)ethoxy)ethanol (160052-24-4) → 2-{[2-(tert-butyldiphenylsilyloxy)ethoxy]acetoxymethyl}-anthraquinone (1265907-08-1)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; sodium bromide / dichloromethane; water / 0.5 h / 0 °C

2: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / water; tert-butyl alcohol / 0 - 20 °C

3: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0 - 20 °C

With dmap; sodium hypochlorite; sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium bromide; In dichloromethane; water; tert-butyl alcohol;

DOI:10.1002/anie.201005161

upstream raw materials:

2-[2-(tert-butyldiphenylsilyloxy)ethoxy]acetic acid

2-Hydroxymethylanthraquinone

2-(2-((tert-butyldiphenylsilyl)oxy)ethoxy)ethanol