Mosher's ester of (R)-5-nitro-2-pentanol

Base Information

Chemical Name:Mosher's ester of (R)-5-nitro-2-pentanol
CAS No.:121314-65-6
Molecular Formula:C₁₅H₁₈F₃NO₅
Molecular Weight:349.307
Hs Code.:

Synonyms:Mosher's ester of (R)-5-nitro-2-pentanol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Mosher's ester of (R)-5-nitro-2-pentanol

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Technology Process of Mosher's ester of (R)-5-nitro-2-pentanol

There total 4 articles about Mosher's ester of (R)-5-nitro-2-pentanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 54045-33-9
rac-5-Nitro-2-pentanol

: 20445-33-4,39637-99-5
(R)-methoxytrifluoromethylphenylacetyl chloride

: 121314-64-5,121314-65-6
(S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid 1-methyl-4-nitro-butyl ester

Guidance literature:: With pyridine; In dichloromethane; for 24h;

Reference yield:

: 54045-33-9
rac-5-Nitro-2-pentanol

: 121314-65-6
Mosher's ester of (R)-5-nitro-2-pentanol

Guidance literature:: Multi-step reaction with 2 steps

2: pyridine / CCl₄

With pyridine; In tetrachloromethane;
DOI:10.1021/ja9616241