N⁶-benzoyl-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine

Base Information

Chemical Name:N⁶-benzoyl-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine
CAS No.:135473-17-5
Molecular Formula:C₃₁H₂₄FN₅O₆
Molecular Weight:581.56
Hs Code.:

N<sup>6</sup>-benzoyl-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine

Synonyms:N⁶-benzoyl-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine

Suppliers and Price of N⁶-benzoyl-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of N⁶-benzoyl-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

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Hazard Codes:

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Technology Process of N⁶-benzoyl-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine

There total 10 articles about N⁶-benzoyl-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 97614-44-3
2-deoxy-2-fluoro-3,5-di-O-benzoyl-α-D-arabinofuranosyl bromide

: 4005-49-6
N-benzoyladenine

: 135473-17-5
N⁶-benzoyl-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine

: N⁶-benzoyl-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-α-D-arabinofuranosyl)adenine

Guidance literature:: N-benzoyladenine; With potassium tert-butylate; In monoethylene glycol diethyl ether; at 0 ℃; for 0.333333h; Inert atmosphere;

2-deoxy-2-fluoro-3,5-di-O-benzoyl-α-D-arabinofuranosyl bromide; With calcium hydride; In 1,2-dichloro-ethane; acetonitrile; at 20 ℃; for 24h; stereoselective reaction; Inert atmosphere;
DOI:10.1016/j.tetlet.2015.11.091

Reference yield: 49.0%

: 97614-44-3
2-deoxy-2-fluoro-3,5-di-O-benzoyl-α-D-arabinofuranosyl bromide

: 4005-49-6
N-benzoyladenine

: 135473-17-5
N⁶-benzoyl-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine

Guidance literature:: N-benzoyladenine; With sodium hydride; In tetrahydrofuran; mineral oil; for 3h; Reflux;

2-deoxy-2-fluoro-3,5-di-O-benzoyl-α-D-arabinofuranosyl bromide; In tetrahydrofuran; mineral oil; at 66 ℃; for 2h;

Reference yield:

: (3S,4R,5R)-5-((benzoyloxy)methyl)-3-fluorotetrahydrofuran-2,4-diyl dibenzoate

: 4005-49-6
N-benzoyladenine

: 135473-17-5
N⁶-benzoyl-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine

Guidance literature:: (3S,4R,5R)-5-((benzoyloxy)methyl)-3-fluorotetrahydrofuran-2,4-diyl dibenzoate; With hydrogen bromide; acetic acid; In dichloromethane; at 0 ℃;

N-benzoyladenine; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; Reflux;

With hydrogenchloride; In dichloromethane; water; at 22 ℃; for 0.5h;