(α-cyclohexylcarbonyl-α-ethoxycarbonylmethylene)triphenylphosphorane

Base Information

• Chemical Name: (α-cyclohexylcarbonyl-α-ethoxycarbonylmethylene)triphenylphosphorane
• CAS No.: 131292-27-8
• Molecular Formula: C₂₉H₃₁O₃P
• Molecular Weight: 458.537
• Mol file: 131292-27-8.mol

Synonyms:(α-cyclohexylcarbonyl-α-ethoxycarbonylmethylene)triphenylphosphorane

Chemical Property of (α-cyclohexylcarbonyl-α-ethoxycarbonylmethylene)triphenylphosphorane

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (α-cyclohexylcarbonyl-α-ethoxycarbonylmethylene)triphenylphosphorane

There total 1 articles about (α-cyclohexylcarbonyl-α-ethoxycarbonylmethylene)triphenylphosphorane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

cyclohexanylcarbonyl chloride (2719-27-9) + ethyl (triphenylphosphoranylidene)acetate (1099-45-2) → (α-cyclohexylcarbonyl-α-ethoxycarbonylmethylene)triphenylphosphorane (131292-27-8)

Guidance literature:

With triethylamine; In toluene; for 3h; Ambient temperature;

Reference yield: 75.0%

(α-cyclohexylcarbonyl-α-ethoxycarbonylmethylene)triphenylphosphorane (131292-27-8) → cyclohexylpropiolic acid (4361-27-7)

Guidance literature:

(α-cyclohexylcarbonyl-α-ethoxycarbonylmethylene)triphenylphosphorane; Heating / reflux;

With potassium hydroxide; ethanol; water; at 20 ℃; for 16h;

With hydrogenchloride; In water; pH=< 2;

Reference yield: 66.0%

(α-cyclohexylcarbonyl-α-ethoxycarbonylmethylene)triphenylphosphorane (131292-27-8) → cyclohexyl-propynoic acid ethyl ester (33547-94-3)

Guidance literature:

at 500 ℃; under 0.1 - 1 Torr;

upstream raw materials:

cyclohexanylcarbonyl chloride

ethyl (triphenylphosphoranylidene)acetate

Downstream raw materials:

2-cyclohexylacetylene

cyclohexyl-propynoic acid ethyl ester

cyclohexylpropiolic acid