1,5-anhydro-3-<<(benzyloxy)methyl>amino>-3,N,4,O-carbonyl-2,3-dideoxy-D-ribo-hex-1-enopyranose

Base Information

Chemical Name:1,5-anhydro-3-<<(benzyloxy)methyl>amino>-3,N,4,O-carbonyl-2,3-dideoxy-D-ribo-hex-1-enopyranose
CAS No.:174290-86-9
Molecular Formula:C₁₅H₁₇NO₅
Molecular Weight:291.304
Hs Code.:

Synonyms:1,5-anhydro-3-<<(benzyloxy)methyl>amino>-3,N,4,O-carbonyl-2,3-dideoxy-D-ribo-hex-1-enopyranose

Suppliers and Price of 1,5-anhydro-3-<<(benzyloxy)methyl>amino>-3,N,4,O-carbonyl-2,3-dideoxy-D-ribo-hex-1-enopyranose

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,5-anhydro-3-<<(benzyloxy)methyl>amino>-3,N,4,O-carbonyl-2,3-dideoxy-D-ribo-hex-1-enopyranose

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,5-anhydro-3-<<(benzyloxy)methyl>amino>-3,N,4,O-carbonyl-2,3-dideoxy-D-ribo-hex-1-enopyranose

There total 6 articles about 1,5-anhydro-3-<<(benzyloxy)methyl>amino>-3,N,4,O-carbonyl-2,3-dideoxy-D-ribo-hex-1-enopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 174290-85-8
1,5-anhydro-3-<<(benzyloxy)methyl>amino>-3,N,4,O-carbonyl-2,3-dideoxy-6-O-(triisopropylsilyl)-D-ribo-hex-1-enopyranose

: 174290-86-9
1,5-anhydro-3-<<(benzyloxy)methyl>amino>-3,N,4,O-carbonyl-2,3-dideoxy-D-ribo-hex-1-enopyranose

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 0.25h;
DOI:10.1021/ja952907g

Reference yield:

: 137915-37-8
1,2-dideoxy-6-O-triisopropylsilyl-D-arabino-1-hexenopyranose

: 174290-86-9
1,5-anhydro-3-<<(benzyloxy)methyl>amino>-3,N,4,O-carbonyl-2,3-dideoxy-D-ribo-hex-1-enopyranose

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) NaH / 1.) CH₂Cl₂, 0 deg C, 30 min, 2.) CH₂Cl₂, RT, overnight

2: BF₃*Et₂O / CH₂Cl₂ / 5 h / -78 °C

3: 80 percent / TsOH*H₂O, Py / H₂O / 14 h / 80 °C

4: 97 percent / NaH / CH₂Cl₂ / Ambient temperature

5: 1.) NaH, 2.) tetrabutylammonium iodide / 1.) DMF, 30 min, 2.) DMF, 40 deg C, 10 h

6: 95 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.25 h

With pyridine; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; tetra-(n-butyl)ammonium iodide; sodium hydride; toluene-4-sulfonic acid; In tetrahydrofuran; dichloromethane; water;
DOI:10.1021/ja952907g

Reference yield:

: 148302-24-3
3-amino-1,5-anhydro-2,3-dideoxy-3,O,4,N-<(trichloromethyl)oxazolino>-6-O-(triisopropylsilyl)-D-ribo-hex-1-enopyranose

: 174290-86-9
1,5-anhydro-3-<<(benzyloxy)methyl>amino>-3,N,4,O-carbonyl-2,3-dideoxy-D-ribo-hex-1-enopyranose

Guidance literature:: Multi-step reaction with 4 steps

1: 80 percent / TsOH*H₂O, Py / H₂O / 14 h / 80 °C

2: 97 percent / NaH / CH₂Cl₂ / Ambient temperature

3: 1.) NaH, 2.) tetrabutylammonium iodide / 1.) DMF, 30 min, 2.) DMF, 40 deg C, 10 h

4: 95 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.25 h

With pyridine; tetrabutyl ammonium fluoride; tetra-(n-butyl)ammonium iodide; sodium hydride; toluene-4-sulfonic acid; In tetrahydrofuran; dichloromethane; water;
DOI:10.1021/ja952907g