1-(benzoylamino)-2-phenylcyclopropanecarboxylic acid

Base Information

• Chemical Name: 1-(benzoylamino)-2-phenylcyclopropanecarboxylic acid
• CAS No.: 4607-84-5
• Molecular Formula: C₁₇H₁₅NO₃
• Molecular Weight: 281.311
• Mol file: 4607-84-5.mol

Synonyms:Cyclopropanecarboxylicacid, 1-benzamido-2-phenyl- (7CI,8CI); NSC 382098

Chemical Property of 1-(benzoylamino)-2-phenylcyclopropanecarboxylic acid

Chemical Property:

• Vapor Pressure: 2.66E-13mmHg at 25°C
• Boiling Point: 558.3°Cat760mmHg
• Flash Point: 291.5°C
• Density: 1.31g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(benzoylamino)-2-phenylcyclopropanecarboxylic acid

There total 13 articles about 1-(benzoylamino)-2-phenylcyclopropanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

methyl 1-benzamido-2-phenyl-cyclopropanecarboxylate (70315-54-7,82112-02-5,82112-03-6,87378-71-0,87378-72-1) → (Z)-1-benzamido-2-phenylcyclopropanecarboxylic acid (4607-84-5,87378-77-6,87378-78-7)

Guidance literature:

With sodium peroxide; In methanol; water; for 6h;

Reference yield:

(Z)-4-benzylidene-2-benzylthio-5(4H)-thiazolone (86557-47-3) → (Z)-1-benzamido-2-phenylcyclopropanecarboxylic acid (4607-84-5,87378-77-6,87378-78-7)

Guidance literature:

Multi-step reaction with 3 steps

1: benzene / 30 - 50 °C

2: KOH / ethanol

3: aq. Na₂CO₃

With potassium hydroxide; sodium carbonate; In ethanol; benzene;

Reference yield:

(Z)-5-benzylthio-1-phenyl-7-oxo-6-thia-4-azaspiro<2.4>hept-4-ene (63140-84-1,86557-55-3,86557-59-7) → (Z)-1-benzamido-2-phenylcyclopropanecarboxylic acid (4607-84-5,87378-77-6,87378-78-7)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH / ethanol

2: aq. Na₂CO₃

With potassium hydroxide; sodium carbonate; In ethanol;

upstream raw materials:

(Z)-1,5-diphenyl-6-oxa-4-azaspiro<2.4>hept-4-en-7-one

4-benzylidene-2-phenyloxazole-5(4H)-one

(E)-(1,5-diphenyl)-7-oxo-6-oxa-4-azaspiro<2.4>hept-4-ene

methyl trans-2-phenyl-1-benzamido-cyclopropane-1-carboxylate

Downstream raw materials:

methyl 1-benzamido-2-phenyl-cyclopropanecarboxylate