5-(3-Trifluoromethylbenzyl)-[1,3,4]thiadiazol-2-ylamine

Base Information

Chemical Name:5-(3-Trifluoromethylbenzyl)-[1,3,4]thiadiazol-2-ylamine
CAS No.:57552-39-3
Molecular Formula:C₁₀H₈F₃N₃S
Molecular Weight:259.255
Hs Code.:
UNII:WCJ4E8GD7H
Wikidata:Q107834463

Synonyms:57552-39-3;5-[3-(Trifluoromethyl)benzyl]-1,3,4-thiadiazol-2-amine;5-(3-(Trifluoromethyl)benzyl)-1,3,4-thiadiazol-2-amine;5-[[3-(trifluoromethyl)phenyl]methyl]-1,3,4-thiadiazol-2-amine;5-{[3-(trifluoromethyl)phenyl]methyl}-1,3,4-thiadiazol-2-amine;5-(3-trifluoromethylbenzyl)-[1,3,4]thiadiazol-2-ylamine;WCJ4E8GD7H;SCHEMBL3467590;RRXDVGPGAOJOFL-UHFFFAOYSA-N;MFCD13873786;LX-0232;SY324461;DB-087413;[5-(3-Trifluoromethylbenzyl)-1,3,4-thiadiazol-2-yl]amine;1,3,4-Thiadiazol-2-amine, 5-[[3-(trifluoromethyl)phenyl]methyl]-

Suppliers and Price of 5-(3-Trifluoromethylbenzyl)-[1,3,4]thiadiazol-2-ylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(3-Trifluoromethylbenzyl)-[1,3,4]thiadiazol-2-ylamine

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:259.03910293
Heavy Atom Count:17
Complexity:262

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)C(F)(F)F)CC2=NN=C(S2)N

Technology Process of 5-(3-Trifluoromethylbenzyl)-[1,3,4]thiadiazol-2-ylamine

There total 3 articles about 5-(3-Trifluoromethylbenzyl)-[1,3,4]thiadiazol-2-ylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 5-(3-trifluoromethylbenzyl)-[1,3,4]thiadiazol-2-ylamine methansulfonate

: 57552-39-3
5-(3-trifluoromethylbenzyl)-[1,3,4]thiadiazol-2-ylamine

Guidance literature:: With sodium hydroxide; In ethyl acetate;

Reference yield: 48.0%

: 351-35-9
3-(trifluoromethyl)phenylacetic acid

: 79-19-6
thiosemicarbazide

: 57552-39-3
5-(3-trifluoromethylbenzyl)-[1,3,4]thiadiazol-2-ylamine

Guidance literature:: 3-(trifluoromethyl)phenylacetic acid; thiosemicarbazide; With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In tetrahydrofuran; at 20 ℃; for 20h;

With methanesulfonic acid; In toluene; for 4h; Reflux;
DOI:10.1016/j.bmcl.2009.05.123