5H-IMIDAZO[2,1-B][1,3]OXAZINE, 6-AZIDO-6,7-DIHYDRO-2-NITRO-, (6S)-

Base Information

Chemical Name:5H-IMIDAZO[2,1-B][1,3]OXAZINE, 6-AZIDO-6,7-DIHYDRO-2-NITRO-, (6S)-
CAS No.:187235-64-9
Molecular Formula:C₆H₆N₆O₃
Molecular Weight:210.152
Hs Code.:
Mol file:187235-64-9.mol

Synonyms:5H-Imidazo[2,1-b][1,3]oxazine,6-azido-6,7-dihydro-2-nitro-, (S)-

Suppliers and Price of 5H-IMIDAZO[2,1-B][1,3]OXAZINE, 6-AZIDO-6,7-DIHYDRO-2-NITRO-, (6S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(6S)-6-AZIDO-6,7-DIHYDRO-2-NITRO-5H-IMIDAZO-[2,1-B][1,3]-OXAZINE 95.00%
5MG
$ 495.28

Total 8 raw suppliers

Chemical Property of 5H-IMIDAZO[2,1-B][1,3]OXAZINE, 6-AZIDO-6,7-DIHYDRO-2-NITRO-, (6S)-

Chemical Property:

Melting Point:152.0-152.4 °C
PSA：122.62000
LogP:0.83856

Purity/Quality:

98%Min ^*data from raw suppliers

(6S)-6-AZIDO-6,7-DIHYDRO-2-NITRO-5H-IMIDAZO-[2,1-B][1,3]-OXAZINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5H-IMIDAZO[2,1-B][1,3]OXAZINE, 6-AZIDO-6,7-DIHYDRO-2-NITRO-, (6S)-

There total 5 articles about 5H-IMIDAZO[2,1-B][1,3]OXAZINE, 6-AZIDO-6,7-DIHYDRO-2-NITRO-, (6S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 187235-13-8
(6R)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-ol

: 187235-64-9
(S)-6-azido-6,7-dihydro-2-nitro-5H-imidazo[2,1-b][1,3]oxazine

Guidance literature:: With di-tert-butyl-diazodicarboxylate; diphenyl phosphoryl azide; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1021/jm801374t

Reference yield: 46.0%

: 1129693-19-1
(R)-6,7-dihydro-2-nitro-5H-imidazo[2,1-b][1,3]oxazin-6-yl methanesulfonate

: 187235-64-9
(S)-6-azido-6,7-dihydro-2-nitro-5H-imidazo[2,1-b][1,3]oxazine

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide; at 70 ℃; for 48h; Inert atmosphere;
DOI:10.1021/jm801374t

Reference yield:

: C₁₀H₁₄N₄O₇

: 187235-64-9
(S)-6-azido-6,7-dihydro-2-nitro-5H-imidazo[2,1-b][1,3]oxazine

Guidance literature:: Multi-step reaction with 5 steps

1: pyridinium p-toluenesulfonate / dichloromethane / 20 °C

2: caesium carbonate / methanol / 0 °C

3: hydrogenchloride / methanol; ethanol; water / 1 h / 20 °C

4: 15 h / 20 °C

5: sodium azide / N,N-dimethyl-formamide / 15 h / 70 °C

With hydrogenchloride; sodium azide; pyridinium p-toluenesulfonate; caesium carbonate; In methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide;