4-Trimethylsilanylmethyl-cyclohex-3-enecarboxylic acid methyl ester

Base Information

• Chemical Name: 4-Trimethylsilanylmethyl-cyclohex-3-enecarboxylic acid methyl ester
• CAS No.: 71092-48-3
• Molecular Formula: C₁₂H₂₂O₂Si
• Molecular Weight: 226.391
• Mol file: 71092-48-3.mol

Synonyms:4-Trimethylsilanylmethyl-cyclohex-3-enecarboxylic acid methyl ester

Chemical Property of 4-Trimethylsilanylmethyl-cyclohex-3-enecarboxylic acid methyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 4-Trimethylsilanylmethyl-cyclohex-3-enecarboxylic acid methyl ester

There total 4 articles about 4-Trimethylsilanylmethyl-cyclohex-3-enecarboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

trimethyl(2-methylenebut-3-enyl)silane (70901-64-3) + acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) → 4-Trimethylsilanylmethyl-cyclohex-3-enecarboxylic acid methyl ester (71092-48-3)

Guidance literature:

With dimethylaluminum chloride; In dichloromethane; at 40 ℃; for 3h;

DOI:10.1021/jo970821v

Reference yield: 75.0%

trimethyl(2-methylenebut-3-enyl)silane (70901-64-3) + acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) → 5-methoxycarbonyl-1-trimethylsilylmethyl-1-cyclohexene (71092-49-4) + 4-Trimethylsilanylmethyl-cyclohex-3-enecarboxylic acid methyl ester (71092-48-3)

Guidance literature:

aluminium trichloride; In benzene; at 50 - 60 ℃; for 2h; without cat. at 80 deg C, 46 h;

DOI:10.1016/S0040-4039(00)86886-0

Reference yield: 38.0%

trimethyl(2-methylenebut-3-enyl)silane (70901-64-3) + acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) → methyl 4-methylenecyclohexane carboxylate (71092-50-7) + 4-Trimethylsilanylmethyl-cyclohex-3-enecarboxylic acid methyl ester (71092-48-3)

Guidance literature:

With titanium tetrachloride; In dichloromethane; at 40 ℃;

DOI:10.1021/jo970821v DOI:10.1021/jo962025f

upstream raw materials:

trimethyl(2-methylenebut-3-enyl)silane

acrylic acid methyl ester

Downstream raw materials:

2-(4-Trimethylsilanylmethyl-cyclohex-3-enyl)-propan-2-ol

methyl 4-methylenecyclohexane carboxylate

δ-terpineol