N-oleoyl-1-O-benzoyl-3-O-(tert-butyldiphenylsilyl)-D-sphingosine (threo epimer)

Base Information

Chemical Name:N-oleoyl-1-O-benzoyl-3-O-(tert-butyldiphenylsilyl)-D-sphingosine (threo epimer)
CAS No.:78779-92-7
Molecular Formula:C₅₉H₉₁NO₄Si
Molecular Weight:906.461
Hs Code.:

Synonyms:N-oleoyl-1-O-benzoyl-3-O-(tert-butyldiphenylsilyl)-D-sphingosine (threo epimer)

Suppliers and Price of N-oleoyl-1-O-benzoyl-3-O-(tert-butyldiphenylsilyl)-D-sphingosine (threo epimer)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of N-oleoyl-1-O-benzoyl-3-O-(tert-butyldiphenylsilyl)-D-sphingosine (threo epimer)

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of N-oleoyl-1-O-benzoyl-3-O-(tert-butyldiphenylsilyl)-D-sphingosine (threo epimer)

There total 8 articles about N-oleoyl-1-O-benzoyl-3-O-(tert-butyldiphenylsilyl)-D-sphingosine (threo epimer) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 78779-90-5
threo-1-O-benzoylceramide

: 58479-61-1
tert-butylchlorodiphenylsilane

: 78779-92-7
N-oleoyl-1-O-benzoyl-3-O-(tert-butyldiphenylsilyl)-D-sphingosine (threo epimer)

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide; 0 to 25 deg C, then 50 deg C;
DOI:10.1021/jo00335a015

Reference yield:

: 765-13-9
pentadec-1-yne

: 78779-92-7
N-oleoyl-1-O-benzoyl-3-O-(tert-butyldiphenylsilyl)-D-sphingosine (threo epimer)

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) DIBAL-H / 2.) ether, toluene, warming from 5 to 23 deg C, 1 h

2: 1.27 g / 2 N HCl / tetrahydrofuran / 16 h / 25 °C

3: pyridine / 16 h / 25 °C

4: 94 percent / imidazole / dimethylformamide / 0 to 25 deg C, then 50 deg C

With pyridine; 1H-imidazole; hydrogenchloride; diisobutylaluminium hydride; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jo00335a015

Reference yield:

: 17363-90-5
p-nitrophenyl oleate

: 78779-92-7
N-oleoyl-1-O-benzoyl-3-O-(tert-butyldiphenylsilyl)-D-sphingosine (threo epimer)

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 16 h / 25 °C

2: 94 percent / imidazole / dimethylformamide / 0 to 25 deg C, then 50 deg C

With pyridine; 1H-imidazole; In N,N-dimethyl-formamide;
DOI:10.1021/jo00335a015