2-Amino-3-(thiazol-4-yl)propanoic acid

Base Information

Chemical Name:2-Amino-3-(thiazol-4-yl)propanoic acid
CAS No.:14717-97-6
Molecular Formula:C₆H₈N₂O₂S
Molecular Weight:172.208
Hs Code.:2934100090
DSSTox Substance ID:DTXSID20561446
Mol file:14717-97-6.mol

Synonyms:14717-97-6;2-Amino-3-(thiazol-4-yl)propanoic acid;DL-4-Thiazolylalanine;2-amino-3-(1,3-thiazol-4-yl)propanoic acid;3-(4-Thiazolyl)-DL-alanine;4-thiazoylalanine;H-DL-Ala(4-Thz)-OH;MFCD00079677;3-(1,3-Thiazol-4-yl)alanine;L-4-thiazoylalanine;d-3-(4-thiazolyl)-alanine;SCHEMBL990478;DTXSID20561446;BCP27435;AKOS012259340;SY254970;WS-00337;CS-0446943;DL-2-Amino-3-(thiazol-4-yl)propanoic acid;A50243;EN300-1237399;A884451

Suppliers and Price of 2-Amino-3-(thiazol-4-yl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Amino-3-(thiazol-4-yl)propanoicacid 95+%
1g
$ 455.00

Chemenu
2-Amino-3-(thiazol-4-yl)propanoicacid 95%
1g
$ 430.00

American Custom Chemicals Corporation
DL-4-THIAZOLYLALANINE 98.00%
5MG
$ 505.75

American Custom Chemicals Corporation
DL-4-THIAZOLYLALANINE 98.00%
1G
$ 975.45

Alichem
2-Amino-3-(thiazol-4-yl)propanoicacid
1g
$ 409.20

Activate Scientific
3-(4-Thiazolyl)-DL-alanine 95+%
25 g
$ 774.00

Activate Scientific
3-(4-Thiazolyl)-DL-alanine 95+%
5 g
$ 257.00

Activate Scientific
3-(4-Thiazolyl)-DL-alanine 95+%
1 g
$ 80.00

Acrotein
3-(4-Thiazolyl)-DL-alanine 97%
1g
$ 55.00

Total 21 raw suppliers

Chemical Property of 2-Amino-3-(thiazol-4-yl)propanoic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:237℃
Refractive Index:1.616
Boiling Point:353.32 °C at 760 mmHg
Flash Point:167.482 °C
PSA：104.45000
Density:1.433 g/cm³
LogP:0.79780
Storage Temp.:2-8°C
XLogP3:-2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:172.03064868
Heavy Atom Count:11
Complexity:154

Purity/Quality:

97% ^*data from raw suppliers

2-Amino-3-(thiazol-4-yl)propanoicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(N=CS1)CC(C(=O)O)N

Technology Process of 2-Amino-3-(thiazol-4-yl)propanoic acid

There total 2 articles about 2-Amino-3-(thiazol-4-yl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 131116-54-6
diethyl (4-thiazolyl)methylacetamidomalonate

: 14717-97-6,131896-42-9
2-Amino-3-(4-thiazolyl)-propanoic acid

Guidance literature:: With hydrogenchloride;
DOI:10.1021/ja01150a502 DOI:10.1021/ja01166a052

Reference yield:

: 14717-97-6,131896-42-9
2-Amino-3-(4-thiazolyl)-propanoic acid

Guidance literature:

Reference yield:

: 14717-97-6,131896-42-9
2-Amino-3-(4-thiazolyl)-propanoic acid

: 108868-88-8
Boc-Phe-dl-(4-thiazolyl)alanine

Guidance literature:: Multi-step reaction with 3 steps

1: SOCl₂ / 15 h / 58 °C

2: N-methylmorpholine / tetrahydrofuran / 18 h

3: 100 percent / LiOH*H₂O / dioxane; H₂O / 0.5 h / 25 °C

With 4-methyl-morpholine; lithium hydroxide; thionyl chloride; In tetrahydrofuran; 1,4-dioxane; water;
DOI:10.1021/jm00390a018