Technology Process of (2Z,4E,8Z,10E)-N-isobutyldodeca-2,4,8,10-tetraenamide
There total 12 articles about (2Z,4E,8Z,10E)-N-isobutyldodeca-2,4,8,10-tetraenamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-N-iso-butyl-2-oxoethyl phosphonium chloride;
With
potassium tert-butylate;
In
tetrahydrofuran;
at 20 ℃;
for 0.5h;
C10H14O;
In
tetrahydrofuran;
at 0 ℃;
for 2h;
DOI:10.1021/jo200289f
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: naphthalene; lithium; zinc(II) chloride / tetrahydrofuran; methanol / 50 °C
2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / -78 - -10 °C
2.2: -78 - 20 °C
3.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / 20 °C
3.2: 2 h / 0 °C
With
oxalyl dichloride; naphthalene; potassium tert-butylate; lithium; dimethyl sulfoxide; zinc(II) chloride;
In
tetrahydrofuran; methanol; dichloromethane;
2.1: Swern oxidation / 2.2: Swern oxidation / 3.1: Wittig reaction / 3.2: Wittig reaction;
DOI:10.1021/jo200289f
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / -78 - -10 °C
1.2: -78 - 20 °C
2.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / 20 °C
2.2: 2 h / 0 °C
With
oxalyl dichloride; potassium tert-butylate; dimethyl sulfoxide;
In
tetrahydrofuran; dichloromethane;
1.1: Swern oxidation / 1.2: Swern oxidation / 2.1: Wittig reaction / 2.2: Wittig reaction;
DOI:10.1021/jo200289f
