bis{2-[m-(2-hydroxyethylthiaisopropyl)α,α-dimethylbenzylcarbamoyl]ethyl} terephthalate

Base Information

• Chemical Name: bis{2-[m-(2-hydroxyethylthiaisopropyl)α,α-dimethylbenzylcarbamoyl]ethyl} terephthalate
• CAS No.: 1356927-83-7
• Molecular Formula: C₄₂H₅₆N₂O₁₀S₂
• Molecular Weight: 813.046
• Mol file: 1356927-83-7.mol

Synonyms:bis{2-[m-(2-hydroxyethylthiaisopropyl)α,α-dimethylbenzylcarbamoyl]ethyl} terephthalate

Chemical Property of bis{2-[m-(2-hydroxyethylthiaisopropyl)α,α-dimethylbenzylcarbamoyl]ethyl} terephthalate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis{2-[m-(2-hydroxyethylthiaisopropyl)α,α-dimethylbenzylcarbamoyl]ethyl} terephthalate

There total 3 articles about bis{2-[m-(2-hydroxyethylthiaisopropyl)α,α-dimethylbenzylcarbamoyl]ethyl} terephthalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C38H44N2O8 (1356927-80-4) + 2-hydroxyethanethiol (60-24-2) → bis{2-[m-(2-hydroxyethylthiaisopropyl)α,α-dimethylbenzylcarbamoyl]ethyl} terephthalate (1356927-83-7)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); In acetonitrile; at 75 ℃; for 4h; Inert atmosphere;

DOI:10.1080/10426507.2011.625512

Reference yield:

1,4-benzenedicarboxylic acid dimethyl ester (120-61-6) → bis{2-[m-(2-hydroxyethylthiaisopropyl)α,α-dimethylbenzylcarbamoyl]ethyl} terephthalate (1356927-83-7)

Guidance literature:

Multi-step reaction with 3 steps

1: zinc diacetate; chloroacetic acid / 24 h / 70 °C

2: dibutyltin dilaurate / tetrahydrofuran / 5 h / 80 °C / Inert atmosphere

3: 2,2'-azobis(isobutyronitrile) / acetonitrile / 4 h / 75 °C / Inert atmosphere

With 2,2'-azobis(isobutyronitrile); zinc diacetate; dibutyltin dilaurate; chloroacetic acid; In tetrahydrofuran; acetonitrile;

DOI:10.1080/10426507.2011.625512

Reference yield:

Bis(2-Hydroxyethyl)terephthalat (959-26-2) + 1-(1-isocyanato-1-methylethyl)-3-(1-methylethenyl)benzene (2094-99-7) → bis{2-[m-(2-hydroxyethylthiaisopropyl)α,α-dimethylbenzylcarbamoyl]ethyl} terephthalate (1356927-83-7)

Guidance literature:

Multi-step reaction with 2 steps

1: dibutyltin dilaurate / tetrahydrofuran / 5 h / 80 °C / Inert atmosphere

2: 2,2'-azobis(isobutyronitrile) / acetonitrile / 4 h / 75 °C / Inert atmosphere

With 2,2'-azobis(isobutyronitrile); dibutyltin dilaurate; In tetrahydrofuran; acetonitrile;

DOI:10.1080/10426507.2011.625512

upstream raw materials:

1,4-benzenedicarboxylic acid dimethyl ester

C₃₈H₄₄N₂O₈

2-hydroxyethanethiol

Bis(2-Hydroxyethyl)terephthalat