(R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-phenylbutanoic acid

Base Information

Chemical Name:(R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-phenylbutanoic acid
CAS No.:209252-16-4
Molecular Formula:C25H23NO4
Molecular Weight:401.45
Hs Code.:2924299090
European Community (EC) Number:805-063-5
DSSTox Substance ID:DTXSID60426702
Nikkaji Number:J1.942.365D
Wikidata:Q72478479
Mol file:209252-16-4.mol

Synonyms:209252-16-4;Fmoc-D-beta-homophenylalanine;(R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-phenylbutanoic acid;(3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-phenylbutanoic acid;(3R)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-4-phenylbutanoic acid;Fmoc-D-beta-Homophe-OH;Fmoc-D-|A-homophenylalanine;(R)-3-(Fmoc-amino)-4-phenylbutyric acid;MFCD04117843;(S)-3-(Fmoc-amino)-4-phenylbutyric acid;(r)-3-(fmoc-amino)-4-phenylbutanoic acid;Fmoc-D-beta-HoPhe-OH;Fmoc-D-Phe-(C#CH2)OH;SCHEMBL119383;DTXSID60426702;Fmoc-D-beta-Homophe-OH, >=96%;AKOS015948793;DS-7826;Benzenebutanoic acid, beta-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (betaR)-;AC-22088;CS-0038390;EN300-637474;F14120;(3R)-3-(9H-Fluorene-9-ylmethoxycarbonylamino)-4-phenylbutanoic acid;(R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-phenylbutanoicacid

Suppliers and Price of (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-phenylbutanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Fmoc-D-beta-homophenylalanine
100mg
$ 363.00

Sigma-Aldrich
Fmoc-D-β-Homophe-OH ≥96%
500mg-f
$ 381.00

Crysdot
(R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-phenylbutanoicacid 97%
5g
$ 422.00

ChemPep
Fmoc-D-β-HoPhe-OH
5g
$ 890.00

ChemPep
Fmoc-D-β-HoPhe-OH
25g
$ 2670.00

Chemenu
Fmoc-D-beta-homophenylalanine 95+%
5g
$ 421.00

Chemenu
Fmoc-D-beta-homophenylalanine 95+%
10g
$ 673.00

Chemenu
Fmoc-D-beta-homophenylalanine 95+%
1g
$ 153.00

BLDpharm
(R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-phenylbutanoicacid 97%
5g
$ 317.00

BLDpharm
(R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-phenylbutanoicacid 97%
1g
$ 105.00

Total 49 raw suppliers

Chemical Property of (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-phenylbutanoic acid

Chemical Property:

Vapor Pressure:6.64E-17mmHg at 25°C
Refractive Index:1.624
Boiling Point:633.2 °C at 760 mmHg
PKA:4.38±0.10(Predicted)
Flash Point:336.8 °C
PSA：75.63000
Density:1.254 g/cm³
LogP:5.00200
Storage Temp.:2-8°C
XLogP3:4.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:401.16270821
Heavy Atom Count:30
Complexity:566

Purity/Quality:

97% ^*data from raw suppliers

Fmoc-D-beta-homophenylalanine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(CC(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
Isomeric SMILES:C1=CC=C(C=C1)C[C@H](CC(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
Uses Fmoc-d-beta-homophenylalanine

Technology Process of (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-phenylbutanoic acid

There total 4 articles about (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-phenylbutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: 203854-65-3
((R)-1-Benzyl-3-diazo-2-oxo-propyl)-carbamic acid 9H-fluoren-9-ylmethyl ester

: 209252-16-4,282524-78-1
Fmoc-β³-(R)-homophenylalanine

Guidance literature:: With silver trifluoroacetate; triethylamine; In tetrahydrofuran; water;
DOI:10.1002/hlca.19980810202

Reference yield:

: 86123-10-6
Fmoc-D-Phe-OH

: 209252-16-4,282524-78-1
Fmoc-β³-(R)-homophenylalanine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) i-BuOCOCl, NMM / 1.) THF, -20 deg C, 20 min, 2.) THF, Et₂O, -5 deg C, 4 h

2: 39 percent / CF₃COOAg, Et₃N / tetrahydrofuran; H₂O

With 4-methyl-morpholine; silver trifluoroacetate; triethylamine; isobutyl chloroformate; In tetrahydrofuran; water;
DOI:10.1002/hlca.19980810202

Reference yield:

: C₂₇H₂₅NO₆

: 209252-16-4,282524-78-1
Fmoc-β³-(R)-homophenylalanine

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran; diethyl ether / 3 h / Ambient temperature

2: silver benzoate, H₂O / dioxane / Ambient temperature

With water; silver benzoate; In tetrahydrofuran; 1,4-dioxane; diethyl ether;
DOI:10.1055/s-1998-2075