2-(3-methoxy-5-methylphenyl)-1,2-dimethylcyclopentane-1-carboxaldehyde

Base Information

• Chemical Name: 2-(3-methoxy-5-methylphenyl)-1,2-dimethylcyclopentane-1-carboxaldehyde
• CAS No.: 929567-91-9
• Molecular Formula: C₁₆H₂₂O₂
• Molecular Weight: 246.349
• Mol file: 929567-91-9.mol

Synonyms:2-(3-methoxy-5-methylphenyl)-1,2-dimethylcyclopentane-1-carboxaldehyde

Chemical Property of 2-(3-methoxy-5-methylphenyl)-1,2-dimethylcyclopentane-1-carboxaldehyde

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2-(3-methoxy-5-methylphenyl)-1,2-dimethylcyclopentane-1-carboxaldehyde

There total 1 articles about 2-(3-methoxy-5-methylphenyl)-1,2-dimethylcyclopentane-1-carboxaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2-(3-methoxy-5-methylphenyl)-1,2-dimethylcyclopentyl-methanol → 2-(3-methoxy-5-methylphenyl)-1,2-dimethylcyclopentane-1-carboxaldehyde (929567-91-9)

Guidance literature:

With pyridinium chlorochromate; In dichloromethane; at 20 ℃; for 0.5h;

DOI:10.1055/s-2006-950355

Reference yield: 59.0%

2-(3-methoxy-5-methylphenyl)-1,2-dimethylcyclopentane-1-carboxaldehyde (929567-91-9) → 5-methyl-3-(1,2,2-trimethylcyclopentyl)anisole (929567-79-3)

Guidance literature:

2-(3-methoxy-5-methylphenyl)-1,2-dimethylcyclopentane-1-carboxaldehyde; With hydrazine hydrate; diethylene glycol; at 125 ℃; for 3h;

With potassium hydroxide; at 190 ℃; for 12h; Further stages.;

DOI:10.1055/s-2006-950355

Reference yield:

2-(3-methoxy-5-methylphenyl)-1,2-dimethylcyclopentane-1-carboxaldehyde (929567-91-9) → 5-methyl-3-(1,2,2-trimethylcyclopentyl)phenol

Guidance literature:

Multi-step reaction with 2 steps

1.1: hydrazine hydrate; digol / 3 h / 125 °C

1.2: 59 percent / KOH / 12 h / 190 °C

2.1: 89 percent / BBr₃ / CH₂Cl₂ / 1 h / 20 °C

With boron tribromide; hydrazine hydrate; diethylene glycol; In dichloromethane;

DOI:10.1055/s-2006-950355

Downstream raw materials:

5-methyl-3-(1,2,2-trimethylcyclopentyl)anisole