4,4-difluoro-8-[4-((3-iodopropoxy)phenyl)]-4-bora-3a,4a-diazaindacene

Base Information

• Chemical Name: 4,4-difluoro-8-[4-((3-iodopropoxy)phenyl)]-4-bora-3a,4a-diazaindacene
• CAS No.: 1374226-10-4
• Molecular Formula: C₁₈H₁₆BF₂IN₂O
• Molecular Weight: 452.05
• Mol file: 1374226-10-4.mol

Synonyms:4,4-difluoro-8-[4-((3-iodopropoxy)phenyl)]-4-bora-3a,4a-diazaindacene

Chemical Property of 4,4-difluoro-8-[4-((3-iodopropoxy)phenyl)]-4-bora-3a,4a-diazaindacene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4-difluoro-8-[4-((3-iodopropoxy)phenyl)]-4-bora-3a,4a-diazaindacene

There total 5 articles about 4,4-difluoro-8-[4-((3-iodopropoxy)phenyl)]-4-bora-3a,4a-diazaindacene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

5-[4-((3-iodopropoxy)phenyl)]dipyrromethene (1374225-56-5) → 4,4-difluoro-8-[4-((3-iodopropoxy)phenyl)]-4-bora-3a,4a-diazaindacene (1374226-10-4)

Guidance literature:

5-[4-((3-iodopropoxy)phenyl)]dipyrromethene; With triethylamine; In toluene; at 70 ℃; for 0.5h; Inert atmosphere;

With boron trifluoride diethyl etherate; In toluene; for 3h; Reflux;

DOI:10.1016/j.dyepig.2012.02.006

Reference yield:

5-[4-((3-iodopropoxy)phenyl)]dipyrromethane (1374225-55-4) → 4,4-difluoro-8-[4-((3-iodopropoxy)phenyl)]-4-bora-3a,4a-diazaindacene (1374226-10-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / methanol; diethyl ether / 0.25 h / 20 °C / Darkness; Inert atmosphere

2.1: triethylamine / toluene / 0.5 h / 70 °C / Inert atmosphere

2.2: 3 h / Reflux

With triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In methanol; diethyl ether; toluene;

DOI:10.1016/j.dyepig.2012.02.006

Reference yield:

4-(3-chloropropoxy)benzaldehyde (82625-25-0) → 4,4-difluoro-8-[4-((3-iodopropoxy)phenyl)]-4-bora-3a,4a-diazaindacene (1374226-10-4)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium iodide / N,N-dimethyl-formamide / 18 h / 80 °C

2.1: trifluoroacetic acid / 0.5 h / 20 °C / Inert atmosphere

3.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / methanol; diethyl ether / 0.25 h / 20 °C / Darkness; Inert atmosphere

4.1: triethylamine / toluene / 0.5 h / 70 °C / Inert atmosphere

4.2: 3 h / Reflux

With triethylamine; trifluoroacetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium iodide; In methanol; diethyl ether; N,N-dimethyl-formamide; toluene;

DOI:10.1016/j.dyepig.2012.02.006

upstream raw materials:

4-(3-iodopropyloxy)benzaldehyde

5-[4-((3-iodopropoxy)phenyl)]dipyrromethane

5-[4-((3-iodopropoxy)phenyl)]dipyrromethene

4-(3-chloropropoxy)benzaldehyde

Downstream raw materials:

C₃₃H₂₇BF₂N₄O₂