ethyl [(3-chloro-2,6-difluorophenyl)(prop-2-en-1-yl)carbamoyl]formate

Base Information

Chemical Name:ethyl [(3-chloro-2,6-difluorophenyl)(prop-2-en-1-yl)carbamoyl]formate
CAS No.:1422511-16-7
Molecular Formula:C₁₃H₁₂ClF₂NO₃
Molecular Weight:303.693
Hs Code.:

Synonyms:ethyl [(3-chloro-2,6-difluorophenyl)(prop-2-en-1-yl)carbamoyl]formate

Suppliers and Price of ethyl [(3-chloro-2,6-difluorophenyl)(prop-2-en-1-yl)carbamoyl]formate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of ethyl [(3-chloro-2,6-difluorophenyl)(prop-2-en-1-yl)carbamoyl]formate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of ethyl [(3-chloro-2,6-difluorophenyl)(prop-2-en-1-yl)carbamoyl]formate

There total 2 articles about ethyl [(3-chloro-2,6-difluorophenyl)(prop-2-en-1-yl)carbamoyl]formate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 1422511-15-6
ethyl [(3-chloro-2,6-difluorophenyl)carbamoyl]formate

: 106-95-6
allyl bromide

: 1422511-16-7
ethyl [(3-chloro-2,6-difluorophenyl)(prop-2-en-1-yl)carbamoyl]formate

Guidance literature:: ethyl [(3-chloro-2,6-difluorophenyl)carbamoyl]formate; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 1h; Inert atmosphere;

allyl bromide; In tetrahydrofuran; at 0 - 20 ℃; for 24h;

Reference yield:

: 287172-82-1
3-chloro-2,6-difluoroaniline

: 1422511-16-7
ethyl [(3-chloro-2,6-difluorophenyl)(prop-2-en-1-yl)carbamoyl]formate

Guidance literature:: Multi-step reaction with 2 steps

1.1: tetrahydrofuran / 0.5 h

2.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 - 20 °C / Inert atmosphere

2.2: 24 h / 0 - 20 °C

With sodium hydride; In tetrahydrofuran; mineral oil;

Reference yield: 83.0%

: 1422511-16-7
ethyl [(3-chloro-2,6-difluorophenyl)(prop-2-en-1-yl)carbamoyl]formate

: 1422511-17-8
ethyl [(3-chloro-2,6-difluorophenyl)(2-oxoethyl)carbamoyl]formate

Guidance literature:: With 2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide; In 1,4-dioxane; water; tert-butyl alcohol; at 20 ℃; for 5h;
DOI:10.1021/acs.jmedchem.0c00464