(10R,11R,1'R)-10,11-bis(methoxymethyl)-5-(8-phenyl-1,2,3,4,-tetrahydro-1-naphthalenyliden-2'-thirrane)-10,11-dihydro-3,7-dibromo-5H-dibenzo[a,d]cycloheptene

Base Information

Chemical Name:(10R,11R,1'R)-10,11-bis(methoxymethyl)-5-(8-phenyl-1,2,3,4,-tetrahydro-1-naphthalenyliden-2'-thirrane)-10,11-dihydro-3,7-dibromo-5H-dibenzo[a,d]cycloheptene
CAS No.:1428654-77-6
Molecular Formula:C₃₅H₃₂Br₂O₂S
Molecular Weight:676.512
Hs Code.:

(10R,11R,1'R)-10,11-bis(methoxymethyl)-5-(8-phenyl-1,2,3,4,-tetrahydro-1-naphthalenyliden-2'-thirrane)-10,11-dihydro-3,7-dibromo-5H-dibenzo[a,d]cycloheptene

Synonyms:(10R,11R,1'R)-10,11-bis(methoxymethyl)-5-(8-phenyl-1,2,3,4,-tetrahydro-1-naphthalenyliden-2'-thirrane)-10,11-dihydro-3,7-dibromo-5H-dibenzo[a,d]cycloheptene

Suppliers and Price of (10R,11R,1'R)-10,11-bis(methoxymethyl)-5-(8-phenyl-1,2,3,4,-tetrahydro-1-naphthalenyliden-2'-thirrane)-10,11-dihydro-3,7-dibromo-5H-dibenzo[a,d]cycloheptene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (10R,11R,1'R)-10,11-bis(methoxymethyl)-5-(8-phenyl-1,2,3,4,-tetrahydro-1-naphthalenyliden-2'-thirrane)-10,11-dihydro-3,7-dibromo-5H-dibenzo[a,d]cycloheptene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (10R,11R,1'R)-10,11-bis(methoxymethyl)-5-(8-phenyl-1,2,3,4,-tetrahydro-1-naphthalenyliden-2'-thirrane)-10,11-dihydro-3,7-dibromo-5H-dibenzo[a,d]cycloheptene

There total 6 articles about (10R,11R,1'R)-10,11-bis(methoxymethyl)-5-(8-phenyl-1,2,3,4,-tetrahydro-1-naphthalenyliden-2'-thirrane)-10,11-dihydro-3,7-dibromo-5H-dibenzo[a,d]cycloheptene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1428654-74-3
C₁₉H₁₈Br₂O₂S

: 1428654-75-4
(E)-(8-phenyl-3,4-dihydronaphthalen-1(2H)-ylidene)hydrazine

: 1428654-77-6
(10R,11R,1'R)-10,11-bis(methoxymethyl)-5-(8-phenyl-1,2,3,4,-tetrahydro-1-naphthalenyliden-2'-thirrane)-10,11-dihydro-3,7-dibromo-5H-dibenzo[a,d]cycloheptene

Guidance literature:: (E)-(8-phenyl-3,4-dihydronaphthalen-1(2H)-ylidene)hydrazine; With magnesium sulfate; potassium hydroxide; silver(l) oxide; In methanol; dichloromethane; at -20 ℃; for 1h; Schlenk technique;

C₁₉H₁₈Br₂O₂S; In dichloromethane; at -20 - 0 ℃; for 16h;
DOI:10.1021/ja401214t

Reference yield:

: 8-phenyl-3,4-dihydro-2H-naphthalen-1-one

: 1428654-77-6
(10R,11R,1'R)-10,11-bis(methoxymethyl)-5-(8-phenyl-1,2,3,4,-tetrahydro-1-naphthalenyliden-2'-thirrane)-10,11-dihydro-3,7-dibromo-5H-dibenzo[a,d]cycloheptene

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrazine hydrate / ethanol / 8 h / Dean-Stark; Reflux

2.1: silver(l) oxide; magnesium sulfate; potassium hydroxide / dichloromethane; methanol / 1 h / -20 °C / Schlenk technique

2.2: 16 h / -20 - 0 °C

With magnesium sulfate; hydrazine hydrate; potassium hydroxide; silver(l) oxide; In methanol; ethanol; dichloromethane;
DOI:10.1021/ja401214t

Reference yield:

: 115474-67-4
(10R,11R)-3,7-dinitro-10,11-bismethoxymethyl-10,11-dihydro-5H-dibenzocycloheptene-5-one

: 1428654-77-6
(10R,11R,1'R)-10,11-bis(methoxymethyl)-5-(8-phenyl-1,2,3,4,-tetrahydro-1-naphthalenyliden-2'-thirrane)-10,11-dihydro-3,7-dibromo-5H-dibenzo[a,d]cycloheptene

Guidance literature:: Multi-step reaction with 4 steps

1.1: tin(ll) chloride / ethanol / 12 h / 80 °C / Inert atmosphere

2.1: sulfuric acid; sodium nitrite / water / 0.5 h

2.2: 3 h / 50 °C

3.1: Lawessons reagent / toluene / Reflux

4.1: silver(l) oxide; magnesium sulfate; potassium hydroxide / dichloromethane; methanol / 1 h / -20 °C / Schlenk technique

4.2: 16 h / -20 - 0 °C

With Lawessons reagent; sulfuric acid; magnesium sulfate; tin(ll) chloride; potassium hydroxide; silver(l) oxide; sodium nitrite; In methanol; ethanol; dichloromethane; water; toluene;
DOI:10.1021/ja401214t