(R*,S*)-(-)-α-(methylenepropyl)cyclohexanemethanol

Base Information

• Chemical Name: (R*,S*)-(-)-α-(methylenepropyl)cyclohexanemethanol
• CAS No.: 167072-96-0
• Molecular Formula: C₁₁H₁₈O
• Molecular Weight: 166.263
• Mol file: 167072-96-0.mol

Synonyms:(R*,S*)-(-)-α-(methylenepropyl)cyclohexanemethanol

Chemical Property of (R*,S*)-(-)-α-(methylenepropyl)cyclohexanemethanol

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (R*,S*)-(-)-α-(methylenepropyl)cyclohexanemethanol

There total 4 articles about (R*,S*)-(-)-α-(methylenepropyl)cyclohexanemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-Cyclohexyl-4-methoxy-but-2-yn-1-one → (R*,S*)-(-)-α-(methylenepropyl)cyclohexanemethanol (167072-96-0)

Guidance literature:

Multi-step reaction with 2 steps

1: (R)-Chirald, LiAlH₄ / diethyl ether / a) -100 deg C, 2 h, b) 0 deg C, 90 min

2: Sm, mercuric chloride / tetrahydrofuran / 4 h / Ambient temperature

With samarium; lithium aluminium tetrahydride; (R)-Chirald; mercury dichloride; In tetrahydrofuran; diethyl ether;

Reference yield:

diiodomethane (75-11-6) + (S)-1-cyclohexyl-buta-2,3-dien-1-ol (109907-84-8,131141-84-9,124563-12-8) → (R,S)-(-)-α-(methylenepropyl)cyclohexanemethanol (150577-80-3) + (R*,S*)-(-)-α-(methylenepropyl)cyclohexanemethanol (167072-96-0)

Guidance literature:

With samarium; mercury dichloride; In tetrahydrofuran; for 4h; Yield given. Yields of byproduct given; Ambient temperature;

Reference yield:

Chloroiodomethane (593-71-5) + (S)-1-cyclohexyl-buta-2,3-dien-1-ol (109907-84-8,131141-84-9,124563-12-8) → (R,S)-(-)-α-(methylenepropyl)cyclohexanemethanol (150577-80-3) + (R*,S*)-(-)-α-(methylenepropyl)cyclohexanemethanol (167072-96-0)

Guidance literature:

With samarium; mercury dichloride; In tetrahydrofuran; for 4h; Yield given. Yields of byproduct given; Ambient temperature;

upstream raw materials:

diiodomethane

(S)-1-cyclohexyl-buta-2,3-dien-1-ol

Chloroiodomethane