2-((prop-2-yn-1-yloxy)methyl)-2-((tosyloxy)methyl)propane-1,3-diyl bis(4-methylbenzenesulfonate)

Base Information

Chemical Name:2-((prop-2-yn-1-yloxy)methyl)-2-((tosyloxy)methyl)propane-1,3-diyl bis(4-methylbenzenesulfonate)
CAS No.:1537223-28-1
Molecular Formula:C₂₉H₃₂O₁₀S₃
Molecular Weight:636.765
Hs Code.:

Synonyms:2-((prop-2-yn-1-yloxy)methyl)-2-((tosyloxy)methyl)propane-1,3-diyl bis(4-methylbenzenesulfonate)

Suppliers and Price of 2-((prop-2-yn-1-yloxy)methyl)-2-((tosyloxy)methyl)propane-1,3-diyl bis(4-methylbenzenesulfonate)

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-((prop-2-yn-1-yloxy)methyl)-2-((tosyloxy)methyl)propane-1,3-diyl bis(4-methylbenzenesulfonate)

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 2-((prop-2-yn-1-yloxy)methyl)-2-((tosyloxy)methyl)propane-1,3-diyl bis(4-methylbenzenesulfonate)

There total 6 articles about 2-((prop-2-yn-1-yloxy)methyl)-2-((tosyloxy)methyl)propane-1,3-diyl bis(4-methylbenzenesulfonate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 32288-04-3
2-(hydroxymethyl)-2-((prop-2-yn-1-yloxy)methyl)propane-1,3-diol

: 98-59-9
p-toluenesulfonyl chloride

: 1537223-28-1
2-((prop-2-yn-1-yloxy)methyl)-2-((tosyloxy)methyl)propane-1,3-diyl bis(4-methylbenzenesulfonate)

Guidance literature:: With pyridine; at -5 - 20 ℃; for 48h;

Reference yield: 87.0%

: 244181-52-0
2-(hydroxymethyl)-2-((tosyloxy)methyl)propanyl-1,3-bis(4'-methylbenzolsulfonate)

: 106-96-7
propargyl bromide

: 1537223-28-1
2-((prop-2-yn-1-yloxy)methyl)-2-((tosyloxy)methyl)propane-1,3-diyl bis(4-methylbenzenesulfonate)

Guidance literature:: With 15-crown-5; sodium hydride; In tetrahydrofuran; toluene; at 0 - 20 ℃; for 21h;
DOI:10.1002/anie.201409803

Reference yield:

: 19309-39-8
1-methyl-4-(hydroxymethyl)-2,6,7-trioxabicyclo-[2.2.2]-octane

: 1537223-28-1
2-((prop-2-yn-1-yloxy)methyl)-2-((tosyloxy)methyl)propane-1,3-diyl bis(4-methylbenzenesulfonate)

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium hydroxide / dimethyl sulfoxide / 0.17 h

1.2: 1.58 h / 0 - 20 °C

2.1: hydrogenchloride / methanol / 16 h / 20 °C

2.2: 24 h / 20 °C

3.1: pyridine / 48 h / -5 - 20 °C

With pyridine; hydrogenchloride; potassium hydroxide; In methanol; dimethyl sulfoxide;