5-fluorobenzofuran-3(2H)-one

Base Information

Chemical Name:5-fluorobenzofuran-3(2H)-one
CAS No.:60770-49-2
Molecular Formula:C8H5 F O2
Molecular Weight:152.125
Hs Code.:2932999099
DSSTox Substance ID:DTXSID70515171
Wikidata:Q72479153
Mol file:60770-49-2.mol

Synonyms:5-fluorobenzofuran-3(2H)-one;60770-49-2;5-Fluoro-benzofuran-3-one;5-Fluorobenzofuran-3-one;5-fluoro-2,3-dihydro-1-benzofuran-3-one;5-Fluoro-1-benzofuran-3(2H)-one;5-fluoro-1-benzofuran-3-one;MFCD08544409;5-Fluorobenzo[b]furan-3(2H)-one;3(2H)-Benzofuranone, 5-fluoro-;5-fluoro-benzofuran -3-one;SCHEMBL3152242;5-fluoro-benzofuran-3(2h)-one;DTXSID70515171;AOFLDWWKVCKMDV-UHFFFAOYSA-N;5-fluoro-benzofuran-3 (2h)-one;AM9389;AKOS000223933;PS-6761;SY011534;A8459;CS-0341589;FT-0657011;EN300-51953;Y13790;Z334863052

Suppliers and Price of 5-fluorobenzofuran-3(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Fluorobenzofuran-3-one
100mg
$ 45.00

SynQuest Laboratories
5-Fluorobenzo[b]furan-3(2H)-one
1 g
$ 144.00

Matrix Scientific
5-Fluorobenzofuran-3(2H)-one 95+%
1g
$ 1143.00

Matrix Scientific
5-Fluorobenzofuran-3(2H)-one 95+%
250mg
$ 530.00

J&W Pharmlab
5-Fluoro-benzofuran-3-one 96%
1g
$ 98.00

J&W Pharmlab
5-Fluoro-benzofuran-3-one 96%
500mg
$ 88.00

J&W Pharmlab
5-Fluoro-benzofuran-3-one 96%
250mg
$ 78.00

J&W Pharmlab
5-Fluoro-benzofuran-3-one 96%
5g
$ 398.00

Crysdot
5-Fluorobenzofuran-3(2H)-one 95+%
10g
$ 637.00

Crysdot
5-Fluorobenzofuran-3(2H)-one 95+%
5g
$ 428.00

Total 24 raw suppliers

Chemical Property of 5-fluorobenzofuran-3(2H)-one

Chemical Property:

PSA：26.30000
LogP:1.40080
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:Chloroform, DMSO (Slightly)
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:152.02735756
Heavy Atom Count:11
Complexity:181

Purity/Quality:

99%, ^*data from raw suppliers

5-Fluorobenzofuran-3-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=O)C2=C(O1)C=CC(=C2)F
Uses 5-Fluorobenzofuran-3-one

Technology Process of 5-fluorobenzofuran-3(2H)-one

There total 11 articles about 5-fluorobenzofuran-3(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.9%

: 1622092-93-6
2-ethynyl-4-fluorophenol

: 60770-49-2
5-fluoro-2,3-dihydro-1-benzofuran-3-one

Guidance literature:: With pyridine N-oxide; mercuric triflate; In dichloromethane; at 20 ℃; for 1h;

Reference yield: 76.0%

: 60770-24-3
2-(carboxymethoxy)-5-fluorobenzoic acid

: 60770-49-2
5-fluoro-2,3-dihydro-1-benzofuran-3-one

Guidance literature:: 2-(carboxymethoxy)-5-fluorobenzoic acid; With sodium acetate; acetic anhydride; at 150 ℃; for 4h;

With hydrogenchloride; water; for 2h; Heating / reflux;

Reference yield: 68.0%

: 912971-79-0
2-ethynyl-4-fluoro-1-methoxybenzene

: 60770-49-2
5-fluoro-2,3-dihydro-1-benzofuran-3-one

Guidance literature:: With methanesulfonic acid; 8-isopropyl-quinoline-N-oxide; (2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl)Au(1H-benzotriazole)NTf₂; In 1,2-dichloro-ethane; at 20 ℃; for 5h;
DOI:10.1002/asia.201403032