{(2R,3S)-3-[(1S,3R)-3-Benzyloxy-3-((2S,3R,5S,6R)-5-benzyloxy-6-benzyloxymethyl-2-methyl-3-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-1-phenylsulfanyl-propoxy]-tetrahydro-pyran-2-yl}-methanol

Base Information

Chemical Name:{(2R,3S)-3-[(1S,3R)-3-Benzyloxy-3-((2S,3R,5S,6R)-5-benzyloxy-6-benzyloxymethyl-2-methyl-3-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-1-phenylsulfanyl-propoxy]-tetrahydro-pyran-2-yl}-methanol
CAS No.:220864-35-7
Molecular Formula:C₅₂H₇₂O₈SSi
Molecular Weight:885.29
Hs Code.:

{(2R,3S)-3-[(1S,3R)-3-Benzyloxy-3-((2S,3R,5S,6R)-5-benzyloxy-6-benzyloxymethyl-2-methyl-3-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-1-phenylsulfanyl-propoxy]-tetrahydro-pyran-2-yl}-methanol

Synonyms:{(2R,3S)-3-[(1S,3R)-3-Benzyloxy-3-((2S,3R,5S,6R)-5-benzyloxy-6-benzyloxymethyl-2-methyl-3-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-1-phenylsulfanyl-propoxy]-tetrahydro-pyran-2-yl}-methanol

Suppliers and Price of {(2R,3S)-3-[(1S,3R)-3-Benzyloxy-3-((2S,3R,5S,6R)-5-benzyloxy-6-benzyloxymethyl-2-methyl-3-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-1-phenylsulfanyl-propoxy]-tetrahydro-pyran-2-yl}-methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of {(2R,3S)-3-[(1S,3R)-3-Benzyloxy-3-((2S,3R,5S,6R)-5-benzyloxy-6-benzyloxymethyl-2-methyl-3-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-1-phenylsulfanyl-propoxy]-tetrahydro-pyran-2-yl}-methanol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of {(2R,3S)-3-[(1S,3R)-3-Benzyloxy-3-((2S,3R,5S,6R)-5-benzyloxy-6-benzyloxymethyl-2-methyl-3-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-1-phenylsulfanyl-propoxy]-tetrahydro-pyran-2-yl}-methanol

There total 15 articles about {(2R,3S)-3-[(1S,3R)-3-Benzyloxy-3-((2S,3R,5S,6R)-5-benzyloxy-6-benzyloxymethyl-2-methyl-3-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-1-phenylsulfanyl-propoxy]-tetrahydro-pyran-2-yl}-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 108-98-5
thiophenol

: 220864-34-6
[(2S,3R,5S,6R)-5-Benzyloxy-2-((R)-1-benzyloxy-2-(2R,4aR,8aS)-hexahydro-pyrano[3,2-d][1,3]dioxin-2-yl-ethyl)-6-benzyloxymethyl-2-methyl-tetrahydro-pyran-3-yloxy]-triisopropyl-silane

: 220864-35-7
{(2R,3S)-3-[(1S,3R)-3-Benzyloxy-3-((2S,3R,5S,6R)-5-benzyloxy-6-benzyloxymethyl-2-methyl-3-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-1-phenylsulfanyl-propoxy]-tetrahydro-pyran-2-yl}-methanol

Guidance literature:: thiophenol; With triethylaluminum; In toluene; at 0 ℃; for 0.5h;

[(2S,3R,5S,6R)-5-Benzyloxy-2-((R)-1-benzyloxy-2-(2R,4aR,8aS)-hexahydro-pyrano[3,2-d][1,3]dioxin-2-yl-ethyl)-6-benzyloxymethyl-2-methyl-tetrahydro-pyran-3-yloxy]-triisopropyl-silane; In dichloromethane; at 20 ℃; for 4.5h; Further stages.;
DOI:10.1021/jo010974p

Reference yield: 79.0%

: 58921-09-8
diethylaluminum benzenethiolate

: 220864-34-6
[(2S,3R,5S,6R)-5-Benzyloxy-2-((R)-1-benzyloxy-2-(2R,4aR,8aS)-hexahydro-pyrano[3,2-d][1,3]dioxin-2-yl-ethyl)-6-benzyloxymethyl-2-methyl-tetrahydro-pyran-3-yloxy]-triisopropyl-silane

: 220864-35-7
{(2R,3S)-3-[(1S,3R)-3-Benzyloxy-3-((2S,3R,5S,6R)-5-benzyloxy-6-benzyloxymethyl-2-methyl-3-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-1-phenylsulfanyl-propoxy]-tetrahydro-pyran-2-yl}-methanol

Guidance literature:: In hexane; dichloromethane; Ambient temperature;
DOI:10.1016/S0040-4039(98)02606-9

Reference yield:

: 80522-42-5
triisopropylsilyl trifluoromethanesulfonate

: 220864-35-7
{(2R,3S)-3-[(1S,3R)-3-Benzyloxy-3-((2S,3R,5S,6R)-5-benzyloxy-6-benzyloxymethyl-2-methyl-3-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-1-phenylsulfanyl-propoxy]-tetrahydro-pyran-2-yl}-methanol

Guidance literature:: Multi-step reaction with 11 steps

1: 2,6-lutidine / CH₂Cl₂ / Ambient temperature

2: CSA / methanol; CH₂Cl₂ / Ambient temperature

3: NaH / dimethylformamide / Ambient temperature

4: OsO₄, NMO / acetone; H₂O / Ambient temperature

5: NaIO₄ / tetrahydrofuran; H₂O / Ambient temperature

6: MgBr₂*OEt₂ / CH₂Cl₂ / -78 - 0 °C

7: NaH / dimethylformamide / Ambient temperature

8: OsO₄, NMO / acetone; H₂O / Ambient temperature

9: NaIO₄ / tetrahydrofuran; H₂O / Ambient temperature

10: Sc(OTf)3 / benzene / Ambient temperature

11: 79 percent / CH₂Cl₂; hexane / Ambient temperature

With 2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide; N-methyl-2-indolinone; camphor-10-sulfonic acid; sodium hydride; magnesium bromide; scandium tris(trifluoromethanesulfonate); In tetrahydrofuran; methanol; hexane; dichloromethane; water; N,N-dimethyl-formamide; acetone; benzene;
DOI:10.1016/S0040-4039(98)02606-9