3-BROMO-2-FUROIC ACID

Base Information

• Chemical Name: 3-BROMO-2-FUROIC ACID
• CAS No.: 14903-90-3
• Molecular Formula: C5H3BrO3
• Molecular Weight: 190.981
• Hs Code.: 2932190090
• Mol file: 14903-90-3.mol

Synonyms:2-Furoicacid, 3-bromo- (8CI);3-Bromo-2-furoic acid;3-Bromofuran-2-carboxylic acid;

Chemical Property of 3-BROMO-2-FUROIC ACID

Chemical Property:

• Vapor Pressure: 0.0021mmHg at 25°C
• Melting Point: 127-129 °C
• Refractive Index: 1.571
• Boiling Point: 278 °C at 760 mmHg
• PKA: 2.77±0.20(Predicted)
• Flash Point: 121.9 °C
• PSA: 50.44000
• Density: 1.891 g/cm³
• LogP: 1.74030
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Bromo-2-furoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 22-26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-BROMO-2-FUROIC ACID

There total 2 articles about 3-BROMO-2-FUROIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-bromofuran-2-carboxylic acid (14903-90-3) + 4-(trifluoromethyl)benzamidoxime (22179-86-8)

Guidance literature:

Reference yield:

→ 3-bromofuran-2-carboxylic acid (14903-90-3) + 4-chlorobenzamidoxime (5033-28-3)

Guidance literature:

Reference yield: 70.0%

3-bromofuran-2-carboxylic acid (14903-90-3) + phenylboronic acid (98-80-6) → 3-phenyl-2-furoic acid (169772-63-8)

Guidance literature:

With sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; for 10h; Reflux;

Downstream raw materials:

(2-Fluoro-furan-3-yl)-phenyl-methanol

(3-bromofuran-2-yl)carbamic acid tert-butyl ester

3-bromo-furan-2-carbonyl chloride

5-(3-bromo-furan-2-yl)-3-(4-chloro-phenyl)-[1,2,4]-oxadiazole

Refernces