4-(5-(4-(5-bromothiophen-2-yl)-2,5-bis(2-ethylhexyl)-3,6-dioxo-2,3,5,6-tetrahydropyrrolo[3,4-c]pyrrol-1-yl)thiophen-2-yl)benzaldehyde

Base Information

• Chemical Name: 4-(5-(4-(5-bromothiophen-2-yl)-2,5-bis(2-ethylhexyl)-3,6-dioxo-2,3,5,6-tetrahydropyrrolo[3,4-c]pyrrol-1-yl)thiophen-2-yl)benzaldehyde
• CAS No.: 1404193-09-4
• Molecular Formula: C₃₇H₄₃BrN₂O₃S₂
• Molecular Weight: 707.796
• Mol file: 1404193-09-4.mol

Synonyms:4-(5-(4-(5-bromothiophen-2-yl)-2,5-bis(2-ethylhexyl)-3,6-dioxo-2,3,5,6-tetrahydropyrrolo[3,4-c]pyrrol-1-yl)thiophen-2-yl)benzaldehyde

Chemical Property of 4-(5-(4-(5-bromothiophen-2-yl)-2,5-bis(2-ethylhexyl)-3,6-dioxo-2,3,5,6-tetrahydropyrrolo[3,4-c]pyrrol-1-yl)thiophen-2-yl)benzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(5-(4-(5-bromothiophen-2-yl)-2,5-bis(2-ethylhexyl)-3,6-dioxo-2,3,5,6-tetrahydropyrrolo[3,4-c]pyrrol-1-yl)thiophen-2-yl)benzaldehyde

There total 3 articles about 4-(5-(4-(5-bromothiophen-2-yl)-2,5-bis(2-ethylhexyl)-3,6-dioxo-2,3,5,6-tetrahydropyrrolo[3,4-c]pyrrol-1-yl)thiophen-2-yl)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

4-(5-(2,5-bis(2-ethylhexyl)-3,6-dioxo-4-(thiophen-2-yl)-2,3,5,6-tetrahydropyrrolo[3,4-c]pyrrol-1-yl)thiophen-2-yl)benzaldehyde (1404193-07-2) → 4-(5-(4-(5-bromothiophen-2-yl)-2,5-bis(2-ethylhexyl)-3,6-dioxo-2,3,5,6-tetrahydropyrrolo[3,4-c]pyrrol-1-yl)thiophen-2-yl)benzaldehyde (1404193-09-4)

Guidance literature:

With N-Bromosuccinimide; In chloroform; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1039/c2cc35125k

Reference yield:

3-(5-bromothiophen-2-yl)-2,5-bis(2-ethylhexyl)-6-(thiophen-2-yl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)dione (1308671-90-0) → 4-(5-(4-(5-bromothiophen-2-yl)-2,5-bis(2-ethylhexyl)-3,6-dioxo-2,3,5,6-tetrahydropyrrolo[3,4-c]pyrrol-1-yl)thiophen-2-yl)benzaldehyde (1404193-09-4)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium phosphate; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; XPhos / toluene; water / 6 h / 80 °C / Inert atmosphere

2: N-Bromosuccinimide / chloroform / 1 h / 20 °C / Inert atmosphere

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; potassium phosphate; N-Bromosuccinimide; XPhos; In chloroform; water; toluene;

DOI:10.1039/c2cc35125k

Reference yield:

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde (128376-64-7) → 4-(5-(4-(5-bromothiophen-2-yl)-2,5-bis(2-ethylhexyl)-3,6-dioxo-2,3,5,6-tetrahydropyrrolo[3,4-c]pyrrol-1-yl)thiophen-2-yl)benzaldehyde (1404193-09-4)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium phosphate; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; XPhos / toluene; water / 6 h / 80 °C / Inert atmosphere

2: N-Bromosuccinimide / chloroform / 1 h / 20 °C / Inert atmosphere

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; potassium phosphate; N-Bromosuccinimide; XPhos; In chloroform; water; toluene;

DOI:10.1039/c2cc35125k

upstream raw materials:

3-(5-bromothiophen-2-yl)-2,5-bis(2-ethylhexyl)-6-(thiophen-2-yl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)dione

4-(5-(2,5-bis(2-ethylhexyl)-3,6-dioxo-4-(thiophen-2-yl)-2,3,5,6-tetrahydropyrrolo[3,4-c]pyrrol-1-yl)thiophen-2-yl)benzaldehyde

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

Downstream raw materials:

C₆₁H₇₇N₃O₅S₂

C₆₇H₈₁N₃O₅S₂

C₆₄H₇₈N₄O₆S₂