3-Hydrazinylpyridazine

Base Information

• Chemical Name: 3-Hydrazinylpyridazine
• CAS No.: 40972-16-5
• Molecular Formula: C4H6N4
• Molecular Weight: 110.118
• Hs Code.: 2933990090
• ChEMBL ID: CHEMBL5176149
• DSSTox Substance ID: DTXSID20485431
• Nikkaji Number: J2.172.873J
• Wikidata: Q72482870
• Mol file: 40972-16-5.mol

Synonyms:3-(bis(2-hydroxyethyl)amino)-6-hydrazinopyridazine;3-hydrazino-6-(N,N-bis(2-hydroxyethyl)amino)pyridazine dihydrochloride;DL 150 IT;hydrazinopyridazine;L 6150;L-6150;oxdralazine;oxdralazine dihydrochloride

Chemical Property of 3-Hydrazinylpyridazine

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.674
• Boiling Point: 399.115 °C at 760 mmHg
• PKA: 6.05±0.20(Predicted)
• Flash Point: 195.178 °C
• PSA: 63.83000
• Density: 1.335 g/cm³
• LogP: 0.53550
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• XLogP3: -0.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 110.059246208
• Heavy Atom Count: 8
• Complexity: 65.1

Purity/Quality:

98%min ^*data from raw suppliers

3-Hydrazinopyridazine hydrochloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=NN=C1)NN

Technology Process of 3-Hydrazinylpyridazine

There total 3 articles about 3-Hydrazinylpyridazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

3-chloropyridazine (1120-95-2) → 3-hydrazinyl pyridazine (40972-16-5)

Guidance literature:

With hydrazine hydrate; In ethanol; Reflux;

DOI:10.1016/j.tetlet.2020.151844

Reference yield:

3-bromopyridazine (88491-61-6) → 3-hydrazinyl pyridazine (40972-16-5)

Guidance literature:

With hydrazine hydrate; In butan-1-ol; for 4h; Mechanism; Heating; also with 15N-labeled hydrazine hydrate;

Reference yield:

→ 3-hydrazinyl pyridazine (40972-16-5)

Guidance literature:

3-Chlor-6-hydrazino-pyridazin, H2/Pd-C, etwas konz. NH3 (Me.);

upstream raw materials:

3-chloropyridazine

3-bromopyridazine

Downstream raw materials:

[1,2,4]Triazolo[4,3-b]pyridazine

3-aminopyridazine

3-pyridazin-3-ylhydrazono-butyric acid ethyl ester

cyclohexanone pyridazin-3-ylhydrazone

Refernces

• 1、 Counotte-Potman, A.,Plas, H. C. van der. "Hydrazination of Pyridazines and Phthalazines". . p. 1259 - 1261. Retrieved 2007/10/02.