Varenicline Impurity 14

Base Information

Chemical Name:Varenicline Impurity 14
CAS No.:230615-59-5
Molecular Formula:C13H10F3N3O5
Molecular Weight:345.235
Hs Code.:
UNII:J4X7FKT7C2
Mol file:230615-59-5.mol

Synonyms:Varenicline Impurity 14;J4X7FKT7C2;SCHEMBL13916008;BDTXJBWOCIFUMR-KNVOCYPGSA-N;2,2,2-Trifluoro-1-(1,2,4,5-tetrahydro-7,8-dinitro-1,5-methano-3H-3-benzazepin-3-yl)ethanone;AC1190;AKOS025311312;1-(4,5-Dinitro-10-azatricyclo[6.3.1.0^2,7^]dodeca-2,4,6-trien-10-yl)-2,2,2-trifluoroethanone;1-[(1S,8R)-4,5-dinitro-10-azatricyclo[6.3.1.02,7]dodeca-2,4,6-trien-10-yl]-2,2,2-trifluoroethanone

Suppliers and Price of Varenicline Impurity 14

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,3,4,5-Tetrahydro-7,8-dinitro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine
1g
$ 1165.00

TRC
2,3,4,5-Tetrahydro-7,8-dinitro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine
500mg
$ 365.00

Matrix Scientific
1-(7,8-Dinitro-4,5-dihydro-1H-1,5-methanobenzo-[d]azepin-3(2H)-yl)-2,2,2-trifluoroethanone 95+%
1g
$ 85.00

Matrix Scientific
1-(7,8-Dinitro-4,5-dihydro-1H-1,5-methanobenzo-[d]azepin-3(2H)-yl)-2,2,2-trifluoroethanone 95+%
5g
$ 322.00

ChemScene
1-(4,5-Dinitro-10-aza-tricyclo[6.3.1.02,7]dodeca-2(7),3,5-trien-10-yl)-2,2,2-trifluoro-ethanone 99.91%
10g
$ 200.00

ChemScene
1-(4,5-Dinitro-10-aza-tricyclo[6.3.1.02,7]dodeca-2(7),3,5-trien-10-yl)-2,2,2-trifluoro-ethanone 99.91%
5g
$ 120.00

ChemScene
1-(4,5-Dinitro-10-aza-tricyclo[6.3.1.02,7]dodeca-2(7),3,5-trien-10-yl)-2,2,2-trifluoro-ethanone 99.91%
25g
$ 425.00

American Custom Chemicals Corporation
2,3,4,5-TETRAHYDRO-7,8-DINITRO-3-(TRIFLUOROACETYL)-1,5-METHANO-1H-3-BENZAZEPINE 95.00%
1G
$ 1686.30

Ambeed
1-(7,8-Dinitro-4,5-dihydro-1H-1,5-methanobenzo[d]azepin-3(2H)-yl)-2,2,2-trifluoroethanone 98%
25g
$ 466.00

Ambeed
1-(7,8-Dinitro-4,5-dihydro-1H-1,5-methanobenzo[d]azepin-3(2H)-yl)-2,2,2-trifluoroethanone 98%
5g
$ 127.00

Total 114 raw suppliers

Chemical Property of Varenicline Impurity 14

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.584
Boiling Point:520.407 °C at 760 mmHg
PKA:-1.93±0.20(Predicted)
Flash Point:268.533 °C
PSA：111.95000
Density:1.605 g/cm³
LogP:3.46270
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:0
Exact Mass:345.05725491
Heavy Atom Count:24
Complexity:537

Purity/Quality:

99% ^*data from raw suppliers

2,3,4,5-Tetrahydro-7,8-dinitro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2CN(CC1C3=CC(=C(C=C23)[N+](=O)[O-])[N+](=O)[O-])C(=O)C(F)(F)F
Isomeric SMILES:C1[C@@H]2CN(C[C@H]1C3=CC(=C(C=C23)[N+](=O)[O-])[N+](=O)[O-])C(=O)C(F)(F)F
Uses Intermediate in the preparation of nicotinic receptor ligand analogs.

Technology Process of Varenicline Impurity 14

There total 3 articles about Varenicline Impurity 14 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.9%