Technology Process of C50H76O16
There total 14 articles about C50H76O16 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C50H78O17;
With
2,4,6-trichlorobenzoyl chloride;
In
tetrahydrofuran;
at 20 ℃;
for 2h;
With
dmap;
In
tetrahydrofuran; toluene;
for 17h;
Further stages.;
Heating;
DOI:10.1021/ol7015115
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 47 percent / TMSOTf / CH2Cl2; acetonitrile / 0.5 h / -50 °C
2.1: aq. LiOH / tetrahydrofuran; methanol / 24 h
3.1: 54 percent / DMAP; DIC / CH2Cl2 / 24 h / 0 - 20 °C
4.1: 70 percent / DDQ / CH2Cl2 / 1 h
5.1: morpholine / Pd(PPh3)4 / tetrahydrofuran / 1 h
6.1: 2,4,6-trichlorobenzoyl chloride / tetrahydrofuran / 2 h / 20 °C
6.2: 6.6 mg / DMAP / tetrahydrofuran; toluene / 17 h / Heating
With
morpholine; dmap; lithium hydroxide; trimethylsilyl trifluoromethanesulfonate; 2,4,6-trichlorobenzoyl chloride; dacarbazine; 2,3-dicyano-5,6-dichloro-p-benzoquinone;
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; methanol; dichloromethane; acetonitrile;
DOI:10.1021/ol7015115
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 47 percent / TMSOTf / CH2Cl2; acetonitrile / 0.5 h / -50 °C
2.1: aq. LiOH / tetrahydrofuran; methanol / 24 h
3.1: 54 percent / DMAP; DIC / CH2Cl2 / 24 h / 0 - 20 °C
4.1: 70 percent / DDQ / CH2Cl2 / 1 h
5.1: morpholine / Pd(PPh3)4 / tetrahydrofuran / 1 h
6.1: 2,4,6-trichlorobenzoyl chloride / tetrahydrofuran / 2 h / 20 °C
6.2: 6.6 mg / DMAP / tetrahydrofuran; toluene / 17 h / Heating
With
morpholine; dmap; lithium hydroxide; trimethylsilyl trifluoromethanesulfonate; 2,4,6-trichlorobenzoyl chloride; dacarbazine; 2,3-dicyano-5,6-dichloro-p-benzoquinone;
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; methanol; dichloromethane; acetonitrile;
DOI:10.1021/ol7015115
