(R)-1-benzyl-3-bromopyrrolidine

Base Information

• Chemical Name: (R)-1-benzyl-3-bromopyrrolidine
• CAS No.: 1246182-98-8
• Molecular Formula: C₁₁H₁₄BrN
• Molecular Weight: 240.143
• Mol file: 1246182-98-8.mol

Synonyms:(R)-1-benzyl-3-bromopyrrolidine

Chemical Property of (R)-1-benzyl-3-bromopyrrolidine

Chemical Property:

Purity/Quality:

(R)-1-Benzyl-3-bromopyrrolidine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-1-benzyl-3-bromopyrrolidine

There total 1 articles about (R)-1-benzyl-3-bromopyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

(S)-N-benzyl-3-hydroxypyrrolidine (101385-90-4) → (R)-1-benzyl-3-bromopyrrolidine (1246182-98-8)

Guidance literature:

(S)-N-benzyl-3-hydroxypyrrolidine; With carbon tetrabromide; In dichloromethane; at -20 ℃; for 0.0833333h;

With triphenylphosphine; In dichloromethane; at -20 - 20 ℃; for 8h;

DOI:10.1002/anie.201001772

Reference yield: 59.0%

(R)-1-benzyl-3-bromopyrrolidine (1246182-98-8) → (S)-1-benzyl-3-pyrrolidine-3-d (1246182-87-5)

Guidance literature:

With lithium aluminium deuteride; In tetrahydrofuran; at 50 ℃; for 10h;

DOI:10.1002/anie.201001772

upstream raw materials:

(S)-N-benzyl-3-hydroxypyrrolidine

Downstream raw materials:

(S)-1-benzyl-3-pyrrolidine-3-d

Refernces