(3R,4R)-methyl 4-aminotetrahydro-2H-pyran-3-carboxylate

Base Information

Chemical Name:(3R,4R)-methyl 4-aminotetrahydro-2H-pyran-3-carboxylate
CAS No.:503168-22-7
Molecular Formula:C7H13 N O3
Molecular Weight:159.18
Hs Code.:2932999099
DSSTox Substance ID:DTXSID70478196
Wikidata:Q82311421
Mol file:503168-22-7.mol

Synonyms:503168-22-7;(3R,4R)-methyl 4-aminotetrahydro-2H-pyran-3-carboxylate;METHYL (3R,4R)-4-AMINOOXANE-3-CARBOXYLATE;MFCD11042298;(3R,4R)-4-AMINOTETRAHYDROPYRAN-3-CARBOXYLIC ACID METHYL ESTER;SCHEMBL3060657;DTXSID70478196;(3R,4R)-4-Amino-tetrahydro-pyran-3-carboxylic acid methyl ester;2H-Pyran-3-carboxylic acid,4-aminotetrahydro-,methyl ester,(3R,4R)-;AKOS006306551;PS-16443;CS-0003868;P18320;(3R,4R)-4-Aminotetrahydropyran-3-carboxylic acid(OMe);(3R,4R)-methyl4-aminotetrahydro-2H-pyran-3-carboxylate;cis-4-Amino-tetrahydro-pyran-3-carboxylic acid methyl ester

Suppliers and Price of (3R,4R)-methyl 4-aminotetrahydro-2H-pyran-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(3R,4R)-4-AMINOTETRAHYDRO-2H-PYRAN-3-CARBOXYLIC ACID METHYL ESTER 95.00%
5MG
$ 503.80

ACHEMBLOCK
(3R,4R)-2H-Pyran-3-carboxylicacid,4-aminotetrahydro-,methylester 95%
5G
$ 2450.00

ACHEMBLOCK
(3R,4R)-2H-Pyran-3-carboxylicacid,4-aminotetrahydro-,methylester 95%
250MG
$ 335.00

Total 15 raw suppliers

Chemical Property of (3R,4R)-methyl 4-aminotetrahydro-2H-pyran-3-carboxylate

Chemical Property:

Vapor Pressure:0.0922mmHg at 25°C
Boiling Point:224.2°C at 760 mmHg
Flash Point:88.6°C
PSA：61.55000
Density:1.115g/cm³
LogP:0.22350
XLogP3:-0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:159.08954328
Heavy Atom Count:11
Complexity:149

Purity/Quality:

99%, ^*data from raw suppliers

(3R,4R)-4-AMINOTETRAHYDRO-2H-PYRAN-3-CARBOXYLIC ACID METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1COCCC1N
Isomeric SMILES:COC(=O)[C@H]1COCC[C@H]1N

Technology Process of (3R,4R)-methyl 4-aminotetrahydro-2H-pyran-3-carboxylate

There total 1 articles about (3R,4R)-methyl 4-aminotetrahydro-2H-pyran-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 477585-11-8
C₁₅H₂₁NO₃

: 503168-22-7,785776-21-8
(3R,4R)-methyl 4-aminotetrahydro-2H-pyran-3-carboxylate

: 785776-21-8
C₇H₁₃NO₃

Guidance literature:: With hydrogenchloride; hydrogen; palladium dihydroxide; In ethanol; Title compound not separated from byproducts.;
DOI:10.1016/j.bmcl.2007.10.093

Reference yield: 97.0%

: 503168-22-7,785776-21-8
(3R,4R)-methyl 4-aminotetrahydro-2H-pyran-3-carboxylate

: 461665-78-1
4-[(2-methyl-4-quinolinyl)methyl]benzoic acid

: 936491-30-4
4-[4-(2-methyl-quinolin-4-ylmethyl)-benzoylamino]-tetrahydro-pyran-3-carboxylic acid methyl ester

Guidance literature:: With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In dichloromethane;
DOI:10.1016/j.bmcl.2007.01.041

Reference yield: 92.0%

: 503168-22-7,785776-21-8
(3R,4R)-methyl 4-aminotetrahydro-2H-pyran-3-carboxylate

: 461666-07-9
4-(2-cyclopropyl-quinolin-4-ylmethyl)-benzoic acid

: 503171-23-1
4-[4-(2-cyclopropyl-quinolin-4-ylmethyl)-benzoylamino]-tetrahydro-pyran-3-carboxylic acid methyl ester

Guidance literature:: With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In dichloromethane;
DOI:10.1016/j.bmcl.2007.01.041