N-[4-{6-[5-ethoxycarbonyl-1-{2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl}-2-propyl-1H-imidazol-4-ylmethylthio]-1-methyl-1H-benzimidazol-2-ylmethoxy}phenylmethyl]-N-(3-trifluoromethylbenzoyl)aminoacetic acid ethyl ester

Base Information

Chemical Name:N-[4-{6-[5-ethoxycarbonyl-1-{2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl}-2-propyl-1H-imidazol-4-ylmethylthio]-1-methyl-1H-benzimidazol-2-ylmethoxy}phenylmethyl]-N-(3-trifluoromethylbenzoyl)aminoacetic acid ethyl ester
CAS No.:1350441-88-1
Molecular Formula:C₅₂H₅₀F₃N₉O₆S
Molecular Weight:986.087
Hs Code.:

N-[4-{6-[5-ethoxycarbonyl-1-{2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl}-2-propyl-1H-imidazol-4-ylmethylthio]-1-methyl-1H-benzimidazol-2-ylmethoxy}phenylmethyl]-N-(3-trifluoromethylbenzoyl)aminoacetic acid ethyl ester

Synonyms:N-[4-{6-[5-ethoxycarbonyl-1-{2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl}-2-propyl-1H-imidazol-4-ylmethylthio]-1-methyl-1H-benzimidazol-2-ylmethoxy}phenylmethyl]-N-(3-trifluoromethylbenzoyl)aminoacetic acid ethyl ester

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Chemical Property of N-[4-{6-[5-ethoxycarbonyl-1-{2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl}-2-propyl-1H-imidazol-4-ylmethylthio]-1-methyl-1H-benzimidazol-2-ylmethoxy}phenylmethyl]-N-(3-trifluoromethylbenzoyl)aminoacetic acid ethyl ester

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Technology Process of N-[4-{6-[5-ethoxycarbonyl-1-{2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl}-2-propyl-1H-imidazol-4-ylmethylthio]-1-methyl-1H-benzimidazol-2-ylmethoxy}phenylmethyl]-N-(3-trifluoromethylbenzoyl)aminoacetic acid ethyl ester

There total 1 articles about N-[4-{6-[5-ethoxycarbonyl-1-{2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl}-2-propyl-1H-imidazol-4-ylmethylthio]-1-methyl-1H-benzimidazol-2-ylmethoxy}phenylmethyl]-N-(3-trifluoromethylbenzoyl)aminoacetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1350441-21-2
N-[4-{4-[5-ethoxycarbonyl-1-{2'-(1-triphenylmethyl-1H-tetrazol-5-yl)biphenyl-4-ylmethyl}-2-propyl-1H-imidazol-4-ylmethylthio]-2-(N-t-butoxycarbonyl-N-methylamino)phenylaminocarbonylmethoxy}phenylmethyl]-N-(3-trifluoromethylbenzoyl)aminoacetic acid ethyl ester

: 1350441-88-1
N-[4-{6-[5-ethoxycarbonyl-1-{2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl}-2-propyl-1H-imidazol-4-ylmethylthio]-1-methyl-1H-benzimidazol-2-ylmethoxy}phenylmethyl]-N-(3-trifluoromethylbenzoyl)aminoacetic acid ethyl ester

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 70 ℃; for 7h;

Reference yield:

: 1350441-88-1
N-[4-{6-[5-ethoxycarbonyl-1-{2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl}-2-propyl-1H-imidazol-4-ylmethylthio]-1-methyl-1H-benzimidazol-2-ylmethoxy}phenylmethyl]-N-(3-trifluoromethylbenzoyl)aminoacetic acid ethyl ester

: 1350439-44-9
N-[4-{6-[5-ethoxycarbonyl-1-{2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl}-2-propyl-1H-imidazol-4-ylmethylthio]-1-methyl-1H-benzimidazol-2-ylmethoxy}phenylmethyl]-N-(3-trifluoromethylbenzoyl)aminoacetic acid

Guidance literature:: N-[4-{6-[5-ethoxycarbonyl-1-{2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl}-2-propyl-1H-imidazol-4-ylmethylthio]-1-methyl-1H-benzimidazol-2-ylmethoxy}phenylmethyl]-N-(3-trifluoromethylbenzoyl)aminoacetic acid ethyl ester; With sodium hydroxide; In tetrahydrofuran; ethanol; at 20 ℃; for 1h;

With hydrogenchloride; In tetrahydrofuran; ethanol; water; ethyl acetate; pH=6;