Benzenemethanamine, 3,5-difluoro-alpha-methyl-, (alphaS)- (9CI)

Base Information

• Chemical Name: Benzenemethanamine, 3,5-difluoro-alpha-methyl-, (alphaS)- (9CI)
• CAS No.: 444643-16-7
• Molecular Formula: C8H9F2N^.HCl
• Molecular Weight: 193.62
• Hs Code.: 2921199990
• Mol file: 444643-16-7.mol

Synonyms:Benzenemethanamine, 3,5-difluoro-alpha-methyl-, (alphaS)- (9CI);Benzenemethanamine, 3,5-difluoro-α-methyl-, (αS)-;Benzenemethanamine, 3,5-difluoro-a-methyl-, (aS)-;(S)-1-(3,5-Difluorophenyl)ethanamine hydrochloride

Chemical Property of Benzenemethanamine, 3,5-difluoro-alpha-methyl-, (alphaS)- (9CI)

Chemical Property:

• PSA: 26.02000
• LogP: 2.68480
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

(αS)-3,5-Difluoro-α-methylbenzenemethanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (αS)-3,5-Difluoro-α-methylbenzenemethanamine was used in the study of practical synthesis of optically active fluorine-substituted α-phenylethylamines by retardation of hydrogenolytic cleavage at benzylic position.

Technology Process of Benzenemethanamine, 3,5-difluoro-alpha-methyl-, (alphaS)- (9CI)

There total 13 articles about Benzenemethanamine, 3,5-difluoro-alpha-methyl-, (alphaS)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

[(S)-1-(3,5-Difluoro-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-amine (444643-14-5) → (S)-1-(3,5-Difluoro-phenyl)-ethylamine (321318-29-0,444643-16-7,771465-40-8)

Guidance literature:

With hydrogen; acetic acid; palladium on activated charcoal; In methanol; at 60 ℃; for 12h; under 3750.3 Torr;

DOI:10.1246/cl.2004.1424

Reference yield:

[(S)-1-(3,5-Difluoro-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-amine (444643-14-5) + [(R)-1-(3,5-Difluoro-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-amine (444643-15-6) → (R)-1-(3,5-difluorophenyl)ethan-1-amine (321318-29-0,444643-16-7,771465-40-8) + (S)-1-(3,5-Difluoro-phenyl)-ethylamine (321318-29-0,444643-16-7,771465-40-8)

Guidance literature:

With hydrogen; 5%-palladium/activated carbon; In methanol; at 60 ℃; for 21h; under 3750.38 Torr; Heating;

Reference yield:

[(S)-1-(3,5-Difluoro-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-amine (444643-14-5) + [(R)-1-(3,5-Difluoro-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-amine (444643-15-6) → (R)-1-(3,5-difluorophenyl)ethan-1-amine (321318-29-0,444643-16-7,771465-40-8) + (S)-1-(3,5-Difluoro-phenyl)-ethylamine (321318-29-0,444643-16-7,771465-40-8)

Guidance literature:

With hydrogen; 5%-palladium/activated carbon; In methanol; at 60 ℃; for 21h; under 3750.38 Torr; Heating;

upstream raw materials:

[(S)-1-(3,5-Difluoro-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-amine

[(R)-1-(3,5-Difluoro-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-amine

1-(3,5-difluorophenyl)ethylamine

3′,5′-difluoroacetophenone

Downstream raw materials:

(R)-1-(3,5-difluorophenyl)ethan-1-amine

3′,5′-difluoroacetophenone

(2R)-5-{(1E)-3-[2-(3,5-difluorophenyl)-5-(fluoromethyl)-2,4,5-trimethyl-6-oxopiperazin-1-yl]prop-1-en-1-yl}-1,3-dihydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one

methyl N-{2-[(tert-butoxycarbonyl)amino]-2-(3,5-difluorophenyl)propyl}-O-[tert-butyl(dimethyl)silyl]-2-methylserinate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 444643-16-7 Benzenemethanamine, 3,5-difluoro-alpha-methyl-, (alphaS)- (9CI)

Send

Send

Metric Ton KG G Pound L ML

Send

Send