Benzenemethanamine, 4-(1,1-dimethylethoxy)-a-methyl-, (S)-

Base Information

Chemical Name:Benzenemethanamine, 4-(1,1-dimethylethoxy)-a-methyl-, (S)-
CAS No.:150575-82-9
Molecular Formula:C12H19 N O
Molecular Weight:193.289
Hs Code.:
Mol file:150575-82-9.mol

Synonyms:Benzenemethanamine, 4-(1,1-dimethylethoxy)-a-methyl-, (S)-;Benzenemethanamine, 4-(1,1-dimethylethoxy)-α-methyl-, (S)- (9CI)

Suppliers and Price of Benzenemethanamine, 4-(1,1-dimethylethoxy)-a-methyl-, (S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
BENZENEMETHANAMINE, 4-(1,1-DIMETHYLETHOXY)-.ALPHA.-METHYL-, (S)- (9CI) 95.00%
5MG
$ 495.21

Total 11 raw suppliers

Chemical Property of Benzenemethanamine, 4-(1,1-dimethylethoxy)-a-methyl-, (S)-

Chemical Property:

PSA：35.25000
LogP:3.58390

Purity/Quality:

98% ^*data from raw suppliers

BENZENEMETHANAMINE, 4-(1,1-DIMETHYLETHOXY)-.ALPHA.-METHYL-, (S)- (9CI) 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzenemethanamine, 4-(1,1-dimethylethoxy)-a-methyl-, (S)-

There total 9 articles about Benzenemethanamine, 4-(1,1-dimethylethoxy)-a-methyl-, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 150494-51-2
N-(carbobenzyloxy)-1(S)-(4-tert-butoxyphenyl)-1-ethylamine

: 150575-82-9,917911-60-5
1(S)-(4-tert-butoxyphenyl)-1-ethylamine

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 4h; under 2585.7 Torr;
DOI:10.1021/jm00068a008

Reference yield:

: 14199-15-6
Methyl 4-hydroxyphenylacetate

: 150575-82-9,917911-60-5
1(S)-(4-tert-butoxyphenyl)-1-ethylamine

Guidance literature:: Multi-step reaction with 9 steps

1: 96 percent / trifluoromethanesulfonic acid / CH₂Cl₂ / 1.) -78 deg C, 15 min, 2.) -20 deg C 45 min

2: 97 percent / aq. 1N NaOH / dioxane / 3 h / Ambient temperature

3: 99 percent / pyridine, cyanuric fluoride / acetonitrile / 2 h / Ambient temperature

4: 1.) 2.5 N BuLi / 1.) THF, hexane, -78 deg C, 15 min, 2.) THF, hexane, -78 deg C, 1 h

5: 1.) 1 N lithium hexamethyldisilazane / 1.) THF, 30 min, 2.) THF, 0 deg C, 1 h

6: 99 percent / lithium peroxide, 30percent H₂O₂, lithium hydroxide monohydrate / tetrahydrofuran; H₂O / 1 h

7: triethylamine, diphenyl phosphorazidate / toluene / 0.5 h / 80 °C

8: 92 percent / 3 h

9: 100 percent / H₂ / 5percent Pd/C / methanol / 4 h / 2585.7 Torr

With pyridine; lithium hydroxide; sodium hydroxide; n-butyllithium; trifluoro-[1,3,5]triazine; lithium peroxide; trifluorormethanesulfonic acid; diphenyl phosphoryl azide; hydrogen; dihydrogen peroxide; triethylamine; lithium hexamethyldisilazane; palladium on activated charcoal; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; toluene; acetonitrile;
DOI:10.1021/jm00068a008

Reference yield:

: 135066-21-6
p-(tert-butoxyphenyl)acetic acid

: 150575-82-9,917911-60-5
1(S)-(4-tert-butoxyphenyl)-1-ethylamine

Guidance literature:: Multi-step reaction with 7 steps

1: 99 percent / pyridine, cyanuric fluoride / acetonitrile / 2 h / Ambient temperature

2: 1.) 2.5 N BuLi / 1.) THF, hexane, -78 deg C, 15 min, 2.) THF, hexane, -78 deg C, 1 h

3: 1.) 1 N lithium hexamethyldisilazane / 1.) THF, 30 min, 2.) THF, 0 deg C, 1 h

4: 99 percent / lithium peroxide, 30percent H₂O₂, lithium hydroxide monohydrate / tetrahydrofuran; H₂O / 1 h

5: triethylamine, diphenyl phosphorazidate / toluene / 0.5 h / 80 °C

6: 92 percent / 3 h

7: 100 percent / H₂ / 5percent Pd/C / methanol / 4 h / 2585.7 Torr

With pyridine; lithium hydroxide; n-butyllithium; trifluoro-[1,3,5]triazine; lithium peroxide; diphenyl phosphoryl azide; hydrogen; dihydrogen peroxide; triethylamine; lithium hexamethyldisilazane; palladium on activated charcoal; In tetrahydrofuran; methanol; water; toluene; acetonitrile;
DOI:10.1021/jm00068a008