4,4,4-trifluoro-N-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-3-(trifluoromethyl)butanamide

Base Information

Chemical Name:4,4,4-trifluoro-N-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-3-(trifluoromethyl)butanamide
CAS No.:1363721-17-8
Molecular Formula:C₈H₅F₁₂NO₂
Molecular Weight:375.114
Hs Code.:

Synonyms:4,4,4-trifluoro-N-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-3-(trifluoromethyl)butanamide

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Chemical Property of 4,4,4-trifluoro-N-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-3-(trifluoromethyl)butanamide

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Technology Process of 4,4,4-trifluoro-N-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-3-(trifluoromethyl)butanamide

There total 3 articles about 4,4,4-trifluoro-N-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-3-(trifluoromethyl)butanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₀H₃₀F₁₂NO₂P

: 814-29-9
Tributylphosphine oxide

: 1363721-17-8
4,4,4-trifluoro-N-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-3-(trifluoromethyl)butanamide

Guidance literature:: With water; In chloroform-d1; at 25 ℃; Inert atmosphere;
DOI:10.1016/j.jfluchem.2011.12.013

Reference yield:

: 1363721-15-6
C₂₃H₂₈F₁₈NO₂P

: 814-29-9
Tributylphosphine oxide

: 1363721-17-8
4,4,4-trifluoro-N-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-3-(trifluoromethyl)butanamide

Guidance literature:: Multi-step reaction with 3 steps

1: water / chloroform-d1 / 25 °C / Inert atmosphere

2: water / chloroform-d1 / 25 °C / Inert atmosphere

3: water / chloroform-d1 / 25 °C / Inert atmosphere

With water; In chloroform-d1;
DOI:10.1016/j.jfluchem.2011.12.013

Reference yield:

: C₂₀H₂₈F₁₂NOP

: 814-29-9
Tributylphosphine oxide

: 1363721-17-8
4,4,4-trifluoro-N-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-3-(trifluoromethyl)butanamide

Guidance literature:: Multi-step reaction with 2 steps

1: water / chloroform-d1 / 25 °C / Inert atmosphere

2: water / chloroform-d1 / 25 °C / Inert atmosphere

With water; In chloroform-d1;
DOI:10.1016/j.jfluchem.2011.12.013