(S)-1-Boc-2-butyl-piperazine

Base Information

Chemical Name:(S)-1-Boc-2-butyl-piperazine
CAS No.:169447-76-1
Molecular Formula:C13H26N2O2
Molecular Weight:242.20
Hs Code.:
DSSTox Substance ID:DTXSID10572485
Wikidata:Q72448810
Mol file:169447-76-1.mol

Synonyms:169447-76-1;(S)-1-Boc-2-butyl-piperazine;(S)-tert-butyl 2-butylpiperazine-1-carboxylate;(S)-1-N-Boc-2-butylpiperazine;tert-butyl (2S)-2-butylpiperazine-1-carboxylate;(S)-1-Boc-2-butylpiperazine;(2s)-1-n-boc-2-butylpiperazine;tert-butyl (S)-2-butylpiperazine-1-carboxylate;SCHEMBL5224956;DTXSID10572485;YWHDUWJBVKOUGW-NSHDSACASA-N;AKOS005259602;AKOS015911881;AC-2213;CS-W020511;CS-13205;(S)-tert-butyl2-butylpiperazine-1-carboxylate;1-tert-Butoxycarbonyl-2(S)-n-butylpiperazine;1-tert-butoxycarbonyl-2(S)-n-butyl-piperazine;A26025;EN300-7142273

Suppliers and Price of (S)-1-Boc-2-butyl-piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-tert-Butyl2-butylpiperazine-1-carboxylate 95+%
1g
$ 353.00

Chemenu
tert-butyl(S)-2-butylpiperazine-1-carboxylate 95%
1g
$ 333.00

Biosynth Carbosynth
(S)-1-Boc-2-butyl-piperazine
250 mg
$ 270.00

Biosynth Carbosynth
(S)-1-Boc-2-butyl-piperazine
100 mg
$ 135.00

Biosynth Carbosynth
(S)-1-Boc-2-butyl-piperazine
50 mg
$ 78.00

Biosynth Carbosynth
(S)-1-Boc-2-butyl-piperazine
1 g
$ 812.50

Biosynth Carbosynth
(S)-1-Boc-2-butyl-piperazine
500 mg
$ 465.00

American Custom Chemicals Corporation
(S)-1-BOC-2-BUTYL-PIPERAZINE 95.00%
5G
$ 1976.78

AK Scientific
(S)-1-Boc-2-butyl-piperazine
50mg
$ 155.00

Activate Scientific
(S)-1-Boc-2-Butyl-piperazine 95+% ee
1 g
$ 216.00

Total 29 raw suppliers

Chemical Property of (S)-1-Boc-2-butyl-piperazine

Chemical Property:

Vapor Pressure:0.000316mmHg at 25°C
Refractive Index:1.459
Boiling Point:320.53 °C at 760 mmHg
PKA:8.49±0.40(Predicted)
Flash Point:147.652 °C
PSA：41.57000
Density:0.964 g/cm³
LogP:2.65220
Storage Temp.:2-8°C(protect from light)
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:242.199428076
Heavy Atom Count:17
Complexity:248

Purity/Quality:

99% ^*data from raw suppliers

(S)-tert-Butyl2-butylpiperazine-1-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCC1CNCCN1C(=O)OC(C)(C)C
Isomeric SMILES:CCCC[C@H]1CNCCN1C(=O)OC(C)(C)C

Technology Process of (S)-1-Boc-2-butyl-piperazine

There total 7 articles about (S)-1-Boc-2-butyl-piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 169447-75-0
4-Benzyl-1-tert-butoxycarbonyl-2(S)-n-butylpiperazine

: 169447-76-1
1-tert-butoxycarbonyl-2(S)-n-butylpiperazine

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 16h;
DOI:10.1021/jm9508090

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 169447-76-1
1-tert-butoxycarbonyl-2(S)-n-butylpiperazine

Guidance literature:: Multi-step reaction with 2 steps

1: CH₂Cl₂ / 2 h

2: 100 percent / H₂ / 10percent Pd/C / methanol / 16 h

With hydrogen; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1021/jm9508090

Reference yield:

: 6404-28-0
Boc-Nle-OH

: 169447-76-1
1-tert-butoxycarbonyl-2(S)-n-butylpiperazine

Guidance literature:: Multi-step reaction with 5 steps

1: 100 percent / DCC / CH₂Cl₂ / 18 h

2: 1.) aq. HCl, 2.) aq. NaHCO₃ / 1.) CHCl₃

3: LiAlH₄ / tetrahydrofuran / 15 h / Heating

4: CH₂Cl₂ / 2 h

5: 100 percent / H₂ / 10percent Pd/C / methanol / 16 h

With hydrogenchloride; lithium aluminium tetrahydride; hydrogen; sodium hydrogencarbonate; dicyclohexyl-carbodiimide; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jm9508090