(S)-1-BOC-3-ISOBUTYLPIPERAZINE

Base Information

• Chemical Name: (S)-1-BOC-3-ISOBUTYLPIPERAZINE
• CAS No.: 928025-62-1
• Molecular Formula: C13H26 N2 O2
• Molecular Weight: 242.362
• Mol file: 928025-62-1.mol

Synonyms:(S)-1-Boc-3-Isobutyl-piperazine ,98%;(3S)-3-(2-Methylpropyl)-1-piperazinecarboxylic acid tert-butyl ester;(S)-tert-Butyl 3-isobutylpiperazine-1-carboxylate

Chemical Property of (S)-1-BOC-3-ISOBUTYLPIPERAZINE

Chemical Property:

• Vapor Pressure: 0.000435mmHg at 25°C
• Boiling Point: 315.5°Cat760mmHg
• Flash Point: 144.6°C
• PSA: 41.57000
• Density: 0.962g/cm³
• LogP: 2.50810
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

99% ^*data from raw suppliers

(S)-tert-Butyl3-isobutylpiperazine-1-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-1-BOC-3-ISOBUTYLPIPERAZINE

There total 1 articles about (S)-1-BOC-3-ISOBUTYLPIPERAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C19H29N3O6S → (3S)-3-isobutylpiperazine-1-carboxylic acid tert-butyl ester (928025-62-1,78551-93-6,928025-61-0)

Guidance literature:

With Octanethiol; 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 20 ℃; for 0.25h; regioselective reaction;

DOI:10.1021/jo900441s

Reference yield: 86.0%

(3S)-3-isobutylpiperazine-1-carboxylic acid tert-butyl ester (928025-62-1,78551-93-6,928025-61-0) + benzyl chloroformate (501-53-1,94274-21-2) → 1-benzyl 4-(tert-butyl) (S)-2-isobutylpiperazine-1,4-dicarboxylate

Guidance literature:

With sodium hydrogencarbonate; In water; acetone; at 0 - 20 ℃; for 5.5h;

Refernces