N-tert-butyl-N-[1-cyclohexyl-2-(4-isopropyl-4,5-dihydrooxazol-2-yl)-2-methylpropyl]hydroxylamine

Base Information

Chemical Name:N-tert-butyl-N-[1-cyclohexyl-2-(4-isopropyl-4,5-dihydrooxazol-2-yl)-2-methylpropyl]hydroxylamine
CAS No.:642481-99-0
Molecular Formula:C₂₀H₃₈N₂O₂
Molecular Weight:338.534
Hs Code.:

Synonyms:N-tert-butyl-N-[1-cyclohexyl-2-(4-isopropyl-4,5-dihydrooxazol-2-yl)-2-methylpropyl]hydroxylamine

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Chemical Property of N-tert-butyl-N-[1-cyclohexyl-2-(4-isopropyl-4,5-dihydrooxazol-2-yl)-2-methylpropyl]hydroxylamine

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Technology Process of N-tert-butyl-N-[1-cyclohexyl-2-(4-isopropyl-4,5-dihydrooxazol-2-yl)-2-methylpropyl]hydroxylamine

There total 1 articles about N-tert-butyl-N-[1-cyclohexyl-2-(4-isopropyl-4,5-dihydrooxazol-2-yl)-2-methylpropyl]hydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 85664-56-8
(Z)-N-(cyclohexylmethylene)-2-methylpropan-2-amine N-oxide

: 93684-73-2
(S)-(-)-4,5-dihydro-2,4-bis(1-methylethyl)oxazole

: 642481-99-0
N-tert-butyl-N-[1-cyclohexyl-2-(4-isopropyl-4,5-dihydrooxazol-2-yl)-2-methylpropyl]hydroxylamine

Guidance literature:: (S)-(-)-4,5-dihydro-2,4-bis(1-methylethyl)oxazole; With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; cyclohexane; at -78 ℃; for 1h;

(Z)-N-(cyclohexylmethylene)-2-methylpropan-2-amine N-oxide; In tetrahydrofuran; cyclohexane; at -78 - 20 ℃;
DOI:10.1021/jo035356i

Reference yield: 80.0%

: 642481-99-0
N-tert-butyl-N-[1-cyclohexyl-2-(4-isopropyl-4,5-dihydrooxazol-2-yl)-2-methylpropyl]hydroxylamine

: (+)-2-tert-butyl-4,4-dimethyl-3-cyclohexylisoxazolidin-5-one

Guidance literature:: With water; oxalic acid; In tetrahydrofuran;
DOI:10.1021/jo035356i

Reference yield:

: 642481-99-0
N-tert-butyl-N-[1-cyclohexyl-2-(4-isopropyl-4,5-dihydrooxazol-2-yl)-2-methylpropyl]hydroxylamine

: (-)-3-tert-butylamino-3-cyclohexyl-2,2-dimethylpropanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / (COOH)2; H₂O / tetrahydrofuran

2: H₂ / Pd/C / methanol / 15001.2 Torr

With water; hydrogen; oxalic acid; palladium on activated charcoal; In tetrahydrofuran; methanol;
DOI:10.1021/jo035356i