(R)-2-(4-bromophenylcarbamoyl)-4-chlorophenyl 2-(benzyloxycarbonylamino)-3-methylbutanoate

Base Information

Chemical Name:(R)-2-(4-bromophenylcarbamoyl)-4-chlorophenyl 2-(benzyloxycarbonylamino)-3-methylbutanoate
CAS No.:1169776-60-6
Molecular Formula:C₂₆H₂₄BrClN₂O₅
Molecular Weight:559.844
Hs Code.:

Synonyms:(R)-2-(4-bromophenylcarbamoyl)-4-chlorophenyl 2-(benzyloxycarbonylamino)-3-methylbutanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-2-(4-bromophenylcarbamoyl)-4-chlorophenyl 2-(benzyloxycarbonylamino)-3-methylbutanoate

Chemical Property:

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Technology Process of (R)-2-(4-bromophenylcarbamoyl)-4-chlorophenyl 2-(benzyloxycarbonylamino)-3-methylbutanoate

There total 1 articles about (R)-2-(4-bromophenylcarbamoyl)-4-chlorophenyl 2-(benzyloxycarbonylamino)-3-methylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

: 1685-33-2
N-[(benzyloxy)carbonyl]-D-valine

: 2627-75-0
N-(4-bromophenyl)-5-chloro-2-hydroxyl benzamide

: 1169776-60-6
(R)-2-(4-bromophenylcarbamoyl)-4-chlorophenyl 2-(benzyloxycarbonylamino)-3-methylbutanoate

Guidance literature:: With dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; at -10 - 4 ℃; for 24h;
DOI:10.1016/j.bmc.2009.04.008

Reference yield:

: 1169776-60-6
(R)-2-(4-bromophenylcarbamoyl)-4-chlorophenyl 2-(benzyloxycarbonylamino)-3-methylbutanoate

: 1227477-00-0
C₁₈H₁₈BrClN₂O₃

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen bromide / acetic acid

2: triethylamine / chloroform

With hydrogen bromide; triethylamine; In chloroform; acetic acid;
DOI:10.3390/molecules16032414