2-[(2S,3R)-2-((S)-2-Oxo-4-phenyl-oxazolidine-3-carbonyl)-3-phenyl-aziridin-1-yl]-isoindole-1,3-dione

Base Information

Chemical Name:2-[(2S,3R)-2-((S)-2-Oxo-4-phenyl-oxazolidine-3-carbonyl)-3-phenyl-aziridin-1-yl]-isoindole-1,3-dione
CAS No.:400889-00-1
Molecular Formula:C₂₆H₁₉N₃O₅
Molecular Weight:453.454
Hs Code.:

Synonyms:2-[(2S,3R)-2-((S)-2-Oxo-4-phenyl-oxazolidine-3-carbonyl)-3-phenyl-aziridin-1-yl]-isoindole-1,3-dione

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Chemical Property of 2-[(2S,3R)-2-((S)-2-Oxo-4-phenyl-oxazolidine-3-carbonyl)-3-phenyl-aziridin-1-yl]-isoindole-1,3-dione

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Technology Process of 2-[(2S,3R)-2-((S)-2-Oxo-4-phenyl-oxazolidine-3-carbonyl)-3-phenyl-aziridin-1-yl]-isoindole-1,3-dione

There total 1 articles about 2-[(2S,3R)-2-((S)-2-Oxo-4-phenyl-oxazolidine-3-carbonyl)-3-phenyl-aziridin-1-yl]-isoindole-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1875-48-5
N-aminophthalamide

: 141209-95-2,146235-33-8
(4S)-4-phenyl-3-[(2E)-3-phenylprop-2-enoyl]-1,3-oxazolidin-2-one

: 400889-00-1
2-[(2S,3R)-2-((S)-2-Oxo-4-phenyl-oxazolidine-3-carbonyl)-3-phenyl-aziridin-1-yl]-isoindole-1,3-dione

: 2-[(2R,3S)-2-((S)-2-Oxo-4-phenyl-oxazolidine-3-carbonyl)-3-phenyl-aziridin-1-yl]-isoindole-1,3-dione

Guidance literature:: With lead(IV) acetate; In dichloromethane; at -20 ℃;

Reference yield: 78.0%

: 400889-00-1
2-[(2S,3R)-2-((S)-2-Oxo-4-phenyl-oxazolidine-3-carbonyl)-3-phenyl-aziridin-1-yl]-isoindole-1,3-dione

: 400889-30-7
2-[(S)-1-Benzyl-2-oxo-2-((S)-2-oxo-4-phenyl-oxazolidin-3-yl)-ethylamino]-isoindole-1,3-dione

Guidance literature:: With hydrogen; triethylamine; palladium on activated charcoal; In ethyl acetate; under 760 Torr;

Reference yield:

: 400889-00-1
2-[(2S,3R)-2-((S)-2-Oxo-4-phenyl-oxazolidine-3-carbonyl)-3-phenyl-aziridin-1-yl]-isoindole-1,3-dione

: (S)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-ylamino)-3-phenyl-propionic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / H₂; Et₃N / 10 percent Pd/C / ethyl acetate / 760 Torr

2: 85 percent / Et₃N / 0.75 h / 20 °C

With hydrogen; triethylamine; palladium on activated charcoal; In ethyl acetate;