(Z)-3-(2,4-Dichloro-phenyl)-3-hydroxy-2-pyridin-2-yl-acrylic acid benzyl ester

Base Information

Chemical Name:(Z)-3-(2,4-Dichloro-phenyl)-3-hydroxy-2-pyridin-2-yl-acrylic acid benzyl ester
CAS No.:347405-67-8
Molecular Formula:C₂₁H₁₅Cl₂NO₃
Molecular Weight:400.261
Hs Code.:

Synonyms:(Z)-3-(2,4-Dichloro-phenyl)-3-hydroxy-2-pyridin-2-yl-acrylic acid benzyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (Z)-3-(2,4-Dichloro-phenyl)-3-hydroxy-2-pyridin-2-yl-acrylic acid benzyl ester

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Technology Process of (Z)-3-(2,4-Dichloro-phenyl)-3-hydroxy-2-pyridin-2-yl-acrylic acid benzyl ester

There total 1 articles about (Z)-3-(2,4-Dichloro-phenyl)-3-hydroxy-2-pyridin-2-yl-acrylic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 118183-57-6
benzyl 2-(pyridin-2-yl)acetate

: 89-75-8
2,4-dichlorobenzoyl chloride

: 347405-67-8
(Z)-3-(2,4-Dichloro-phenyl)-3-hydroxy-2-pyridin-2-yl-acrylic acid benzyl ester

Guidance literature:: benzyl 2-(pyridin-2-yl)acetate; With lithium diisopropyl amide; In diethyl ether; hexane; at -78 ℃; for 1h;

2,4-dichlorobenzoyl chloride; In diethyl ether; hexane; at 0 ℃; for 0.5h; Further stages.;
DOI:10.1039/b009172n