Technology Process of C17H12INO
There total 5 articles about C17H12INO which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tris(triphenylphosphine)ruthenium(II) chloride;
In
isopropyl alcohol;
at 80 ℃;
for 36h;
Inert atmosphere;
Schlenk technique;
DOI:10.1021/ol400223d
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium azide; boron trifluoride diethyl etherate; trifluoroacetic acid / dichloromethane / 0.5 h / 0 - 20 °C
2: tris(triphenylphosphine)ruthenium(II) chloride / isopropyl alcohol / 36 h / 80 °C / Inert atmosphere; Schlenk technique
With
tris(triphenylphosphine)ruthenium(II) chloride; sodium azide; boron trifluoride diethyl etherate; trifluoroacetic acid;
In
dichloromethane; isopropyl alcohol;
DOI:10.1021/ol400223d
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium hydride / tetrahydrofuran; mineral oil / 16 h / Reflux
2: potassium carbonate / dimethyl sulfoxide / 20 °C
3: sodium azide; boron trifluoride diethyl etherate; trifluoroacetic acid / dichloromethane / 0.5 h / 0 - 20 °C
4: tris(triphenylphosphine)ruthenium(II) chloride / isopropyl alcohol / 36 h / 80 °C / Inert atmosphere; Schlenk technique
With
tris(triphenylphosphine)ruthenium(II) chloride; sodium azide; boron trifluoride diethyl etherate; sodium hydride; potassium carbonate; trifluoroacetic acid;
In
tetrahydrofuran; dichloromethane; dimethyl sulfoxide; isopropyl alcohol; mineral oil;
1: |Claisen Condensation;
DOI:10.1021/ol400223d
