(1R,2R)-(-)-N,N'-Dimethylcyclohexane-1,2-diamine

Base Information

Chemical Name:(1R,2R)-(-)-N,N'-Dimethylcyclohexane-1,2-diamine
CAS No.:67579-81-1
Molecular Formula:C8H18 N2
Molecular Weight:142.244
Hs Code.:2921309990
European Community (EC) Number:614-082-6,626-704-3
DSSTox Substance ID:DTXSID20986938
Nikkaji Number:J596.263C
Wikidata:Q72469663

Synonyms:trans-N,N'-dimethyl-1,2-cyclohexanediamine

Suppliers and Price of (1R,2R)-(-)-N,N'-Dimethylcyclohexane-1,2-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
trans-(1R,2R)-N,N’-Bismethyl-1,2-cyclohexanediamine
5g
$ 185.00

TCI Chemical
trans-N,N'-Dimethylcyclohexane-1,2-diamine >98.0%(T)
5g
$ 76.00

TCI Chemical
trans-N,N'-Dimethylcyclohexane-1,2-diamine >98.0%(T)
1g
$ 26.00

SynQuest Laboratories
trans-N,N'-Dimethylcyclohexane-1,2-diamine 95%
25 g
$ 296.00

SynQuest Laboratories
trans-N,N'-Dimethylcyclohexane-1,2-diamine 95%
1 g
$ 39.00

SynQuest Laboratories
trans-N,N'-Dimethylcyclohexane-1,2-diamine 95%
5 g
$ 93.00

Strem Chemicals
trans-N,N'-Dimethyl-1,2-cyclohexanediamine, 98%
2g
$ 116.00

Strem Chemicals
trans-N,N'-Dimethyl-1,2-cyclohexanediamine, 98%
500mg
$ 53.00

Strem Chemicals
trans-N,N'-Dimethyl-1,2-cyclohexanediamine, 98%
10g
$ 466.00

Sigma-Aldrich
trans-N,N′-Dimethylcyclohexane-1,2-diamine 97%
100ml
$ 2190.00

Total 117 raw suppliers

Chemical Property of (1R,2R)-(-)-N,N'-Dimethylcyclohexane-1,2-diamine

Chemical Property:

Melting Point:4°C
Refractive Index:n20/D1.472(lit.)
Boiling Point:83 °C / 13mmHg
PKA:11.04±0.40(Predicted)
Flash Point:60℃
PSA：24.06000
Density:0.89
LogP:1.51820
Storage Temp.:Refrigerator
Sensitive.:air sensitive
XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:142.146998583
Heavy Atom Count:10
Complexity:81.3

Purity/Quality:

99%, ^*data from raw suppliers

trans-(1R,2R)-N,N’-Bismethyl-1,2-cyclohexanediamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:C
Statements: 36/37/38-34-22
Safety Statements: 26-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC1CCCCC1NC
Isomeric SMILES:CN[C@@H]1CCCC[C@H]1NC
Uses Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine used with CuI to form a general and highly efficient catalyst for the N-amidation of aryl and heteroaryl iodides, bromides and in some cases, unactivated aryl chlorides. The catalyst system is also used for the N-arylation of indoles. trans-N,N′-dimethylcyclohexane-1,2-diamine can be used as a ligand in the synthesis of the following products via copper catalyzed C-N coupling reactions:vinylsulfoximines obtained from NH sulfoximes and vinyl bromidesN-arylpyridones obtained via reaction between 2-substituted pyridines and aryl halidesN-aryl amines obtained via reaction between amines and aryl iodides/aryl bromides
Description Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine is a useful research chemical for organic synthesis and other chemical processes.

Technology Process of (1R,2R)-(-)-N,N'-Dimethylcyclohexane-1,2-diamine

There total 17 articles about (1R,2R)-(-)-N,N'-Dimethylcyclohexane-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: N,N’-[(±)-trans-cyclohexane-1,2-diyl]diformamide

: 61798-24-1,67579-81-1,68737-65-5,75599-23-4,87583-89-9,99295-66-6
trans-N,N'-dimethylcyclohexane-1,2-diamine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 65 ℃; for 16h;
DOI:10.1021/ja027433h

Reference yield: 88.0%

: trans-1,2-bis(ethoxycarbonylamino)cyclohexane

: 67579-81-1
trans-N,N'-dimethyl-1,2-cyclohexyldiamine

Guidance literature:: trans-1,2-bis(ethoxycarbonylamino)cyclohexane; With lithium aluminium tetrahydride; In tetrahydrofuran; at 5 - 20 ℃; Heating / reflux;

With sodium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 1h; Heating / reflux;

Reference yield: 42.0%

: 61798-24-1,67579-81-1,68737-65-5,75599-23-4,87583-89-9,99295-66-6
trans-N,N'-dimethylcyclohexane-1,2-diamine

: 61798-24-1,67579-81-1,68737-65-5,75599-23-4,99295-66-6,87583-89-9
(1S,2S)-N,N'-dimethyl-1,2-diaminocyclohexane

Guidance literature:: trans-N,N'-dimethylcyclohexane-1,2-diamine; With L-Tartaric acid; In ethanol; at 20 ℃; for 1h; Reflux; Resolution of racemate;

With potassium hydroxide; In dichloromethane; at 20 ℃; pH=9-10; Reflux; Resolution of racemate;
DOI:10.3184/174751913X13626731204890