R-1,1'-BINAPHTHYL-2,2'-DICARBOXYLIC ACID

Base Information

• Chemical Name: R-1,1'-BINAPHTHYL-2,2'-DICARBOXYLIC ACID
• CAS No.: 80703-23-7
• Molecular Formula: C₂₂H₁₄O₄
• Molecular Weight: 342.351
• Mol file: 80703-23-7.mol

Synonyms:[1,1'-binaphthalene]-2,2'-dicarboxylic acid;1,1'-binaphthyl-2,2'-dicarboxylic acid;

Chemical Property of R-1,1'-BINAPHTHYL-2,2'-DICARBOXYLIC ACID

Chemical Property:

• Boiling Point: 493.3 °C at 760 mmHg
• PKA: 3.66±0.30(Predicted)
• Flash Point: 266.2 °C
• PSA: 74.60000
• Density: 1.38 g/cm³
• LogP: 5.05640

Purity/Quality:

99% ^*data from raw suppliers

R-1,1'-BINAPHTHYL-2,2'-DICARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of R-1,1'-BINAPHTHYL-2,2'-DICARBOXYLIC ACID

There total 89 articles about R-1,1'-BINAPHTHYL-2,2'-DICARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

carbon dioxide (124-38-9,18923-20-1) + 2,2'-dibromo-1,1'-binaphthyl (74866-28-7,86688-08-6,150024-49-0) → 1,1'-binaphthyl-2,2'-dicarboxylic acid (18531-96-9,80703-23-7,99827-46-0)

Guidance literature:

2,2'-dibromo-1,1'-binaphthyl; With tert.-butyl lithium; In tetrahydrofuran; pentane; at -78 ℃; for 1h;

carbon dioxide; In tetrahydrofuran; pentane; at -78 - 20 ℃; for 12.05h;

Reference yield: 91.0%

[1,1′-binaphthalene]-2,2′-dicarboxaldehyde (161146-88-9) → 1,1'-binaphthyl-2,2'-dicarboxylic acid (18531-96-9,80703-23-7,99827-46-0)

Guidance literature:

With sodium chlorite; sodium dihydrogenphosphate; dihydrogen peroxide; In acetonitrile; at 50 ℃; for 0.75h;

DOI:10.1021/ja066462f

Reference yield: 90.0%

[1,1']binaphthyl-2,2'-dicarboxylic acid dimethyl ester (85464-88-6,113567-15-0,113567-21-8) → 1,1'-binaphthyl-2,2'-dicarboxylic acid (18531-96-9,80703-23-7,99827-46-0)

Guidance literature:

With potassium hydroxide; In methanol; for 14h; Heating;

DOI:10.1021/ja00050a011

upstream raw materials:

1,1'-binaphthalene-2,2'-diamine

[1,1']binaphthyl-2,2'-dicarboxylic acid dimethyl ester

Methyl 1-chloro-2-naphthoate

2,2'-bis[2-(4,4-dimethyl-Δ²-oxazolinyl)]-1,1'-binaphthyl

Downstream raw materials:

anthanthrone

(S)-1,1'-binaphthyl-2,2'-dicarboxylic acid

(R)-1,1'-binaphthyl-2,2'-dicarboxylic acid

rac-2,2'-Binaphthyldicarboxylic acid dichloride