methyl N-α,N^G,N^G-tris(benzyloxycarbonyl)-L-arginyl-L-norvalyl>-8-amino-2,6-anhydro-3,8-dideoxy-glycero-D-talo-octonate

Base Information

• Chemical Name: methyl N-α,N^G,N^G-tris(benzyloxycarbonyl)-L-arginyl-L-norvalyl>-8-amino-2,6-anhydro-3,8-dideoxy-glycero-D-talo-octonate
• CAS No.: 110512-44-2
• Molecular Formula: C₄₄H₅₆N₆O₁₄
• Molecular Weight: 892.96

Synonyms:methyl N-α,N^G,N^G-tris(benzyloxycarbonyl)-L-arginyl-L-norvalyl>-8-amino-2,6-anhydro-3,8-dideoxy-glycero-D-talo-octonate

Chemical Property of methyl N-α,N^G,N^G-tris(benzyloxycarbonyl)-L-arginyl-L-norvalyl>-8-amino-2,6-anhydro-3,8-dideoxy-glycero-D-talo-octonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl N-α,N^G,N^G-tris(benzyloxycarbonyl)-L-arginyl-L-norvalyl>-8-amino-2,6-anhydro-3,8-dideoxy-glycero-D-talo-octonate

There total 7 articles about methyl N-α,N^G,N^G-tris(benzyloxycarbonyl)-L-arginyl-L-norvalyl>-8-amino-2,6-anhydro-3,8-dideoxy-glycero-D-talo-octonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

methyl N-L-norvalyl-8-amino-2,6-anhydro-3,8-dideoxy-D-glycero-D-talo-octonate (110512-53-3) + Nα,NG,NG-tri-Cbz-L-arginine succinimido ester (50715-13-4) → methyl N-α,NG,NG-tris(benzyloxycarbonyl)-L-arginyl-L-norvalyl>-8-amino-2,6-anhydro-3,8-dideoxy-glycero-D-talo-octonate (110512-44-2)

Guidance literature:

In tetrahydrofuran; methanol; for 2h; Ambient temperature;

DOI:10.1021/jm00395a022

Reference yield:

N-<(benzyloxycarbonyl)-(S)-norvalyl>succinimide (71447-85-3) → methyl N-α,NG,NG-tris(benzyloxycarbonyl)-L-arginyl-L-norvalyl>-8-amino-2,6-anhydro-3,8-dideoxy-glycero-D-talo-octonate (110512-44-2)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrahydrofuran; methanol / 2 h / Ambient temperature

2: H₂ / 10percent Pd/C / methanol

3: 49 percent / tetrahydrofuran; methanol / 2 h / Ambient temperature

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol;

DOI:10.1021/jm00395a022

Reference yield:

Z-L-norvaline (21691-44-1) → methyl N-α,NG,NG-tris(benzyloxycarbonyl)-L-arginyl-L-norvalyl>-8-amino-2,6-anhydro-3,8-dideoxy-glycero-D-talo-octonate (110512-44-2)

Guidance literature:

Multi-step reaction with 4 steps

1: dicyclocarbodiimide / tetrahydrofuran / 0 - 5 °C

2: tetrahydrofuran; methanol / 2 h / Ambient temperature

3: H₂ / 10percent Pd/C / methanol

4: 49 percent / tetrahydrofuran; methanol / 2 h / Ambient temperature

With hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal; In tetrahydrofuran; methanol;

DOI:10.1021/jm00395a022

upstream raw materials:

methyl N-L-norvalyl-8-amino-2,6-anhydro-3,8-dideoxy-D-glycero-D-talo-octonate

N^α,N^G,N^G-tri-Cbz-L-arginine succinimido ester

N-<(benzyloxycarbonyl)-(S)-norvalyl>succinimide

Z-L-norvaline

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 110512-44-2 methyl N-α,N^G,N^G-tris(benzyloxycarbonyl)-L-arginyl-L-norvalyl>-8-amino-2,6-anhydro-3,8-dideoxy-glycero-D-talo-octonate

Send

Send

Metric Ton KG G Pound L ML

Send

Send